COVID-19 and diabetes mellitus: from pathophysiology to clinical management

S Lim, JH Bae, HS Kwon, MA Nauck - Nature Reviews Endocrinology, 2021 - nature.com
Initial studies found increased severity of coronavirus disease 2019 (COVID-19), caused by
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in patients …

Recent developments on therapeutic and diagnostic approaches for COVID-19

J Majumder, T Minko - The AAPS journal, 2021 - Springer
The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made a serious public health …

Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis

F Kabinger, C Stiller, J Schmitzová… - Nature structural & …, 2021 - nature.com
Molnupiravir is an orally available antiviral drug candidate currently in phase III trials for the
treatment of patients with COVID-19. Molnupiravir increases the frequency of viral RNA …

Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms

LJ Stevens, AJ Pruijssers, HW Lee… - Science translational …, 2022 - science.org
The nucleoside analog remdesivir (RDV) is a Food and Drug Administration–approved
antiviral for treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19

B Boras, RM Jones, BJ Anson, D Arenson… - Nature …, 2021 - nature.com
COVID-19 caused by the SARS-CoV-2 virus has become a global pandemic. 3CL protease
is a virally encoded protein that is essential across a broad spectrum of coronaviruses with …

[HTML][HTML] Attributes and predictors of long COVID

CH Sudre, B Murray, T Varsavsky, MS Graham… - Nature medicine, 2021 - nature.com
Reports of long-lasting coronavirus disease 2019 (COVID-19) symptoms, the so-called 'long
COVID', are rising but little is known about prevalence, risk factors or whether it is possible to …

COVID-19: breaking down a global health crisis

SI Mallah, OK Ghorab, S Al-Salmi, OS Abdellatif… - Annals of clinical …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is the second pandemic of the twenty-first
century, with over one-hundred million infections and over two million deaths to date. It is a …

[HTML][HTML] Characteristics of SARS-CoV-2 and COVID-19

B Hu, H Guo, P Zhou, ZL Shi - Nature reviews microbiology, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute …

[HTML][HTML] Effect of tocilizumab vs usual care in adults hospitalized with COVID-19 and moderate or severe pneumonia: a randomized clinical trial

O Hermine, X Mariette, PL Tharaux… - JAMA internal …, 2021 - jamanetwork.com
Importance Severe pneumonia with hyperinflammation and elevated interleukin-6 is a
common presentation of coronavirus disease 2019 (COVID-19). Objective To determine …

COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup

MK Nadim, LG Forni, RL Mehta, MJ Connor Jr… - Nature reviews …, 2020 - nature.com
Kidney involvement in patients with coronavirus disease 2019 (COVID-19) is common, and
can range from the presence of proteinuria and haematuria to acute kidney injury (AKI) …