Effect of physical activity/exercise on oxidative stress and inflammation in muscle and vascular aging

M El Assar, A Álvarez-Bustos, P Sosa, J Angulo… - International Journal of …, 2022 - mdpi.com
Functional status is considered the main determinant of healthy aging. Impairment in
skeletal muscle and the cardiovascular system, two interrelated systems, results in …

Mouse models of atherosclerosis and their suitability for the study of myocardial infarction

P Golforoush, DM Yellon, SM Davidson - Basic research in cardiology, 2020 - Springer
Atherosclerotic plaques impair vascular function and can lead to arterial obstruction and
tissue ischaemia. Rupture of an atherosclerotic plaque within a coronary artery can result in …

Porous molybdenum nitride nanosphere as carrier-free and efficient nitric oxide donor for synergistic nitric oxide and chemo/sonodynamic therapy

Q Bai, M Wang, J Liu, X Sun, P Yang, F Qu, H Lin - ACS nano, 2023 - ACS Publications
Given its abundant physiological functions, nitric oxide (NO) has attracted much attention as
a cancer therapy. The sensitive release and great supply capacity are significant indicators …

NO donors as the wonder molecules with therapeutic potential: Recent trends and future perspectives

GR Navale, S Singh, K Ghosh - Coordination Chemistry Reviews, 2023 - Elsevier
Nitric oxide (NO), an endogenous, free radical, highly unstable, diatomic gaseous molecule,
plays crucial roles in several physiological and pathological processes. It has attracted …

How periodontal disease and presence of nitric oxide reducing oral bacteria can affect blood pressure

P Pignatelli, G Fabietti, A Ricci, A Piattelli… - International journal of …, 2020 - mdpi.com
Nitric oxide (NO), a small gaseous and multifunctional signaling molecule, is involved in the
maintenance of metabolic and cardiovascular homeostasis. It is endogenously produced in …

Recent progress in nitric oxide-generating nanomedicine for cancer therapy

Y Li, B Yoon, A Dey, JH Park - Journal of Controlled Release, 2022 - Elsevier
Nitric oxide (NO) is an endogenous, multipotent biological signaling molecule that
participates in several physiological processes. Recently, exogenous supplementation of …

Synthetic, natural, and semisynthetic polymer carriers for controlled nitric oxide release in dermal applications: a review

C Gutierrez Cisneros, V Bloemen, A Mignon - Polymers, 2021 - mdpi.com
Nitric oxide (NO•) is a free radical gas, produced in the human body to regulate
physiological processes, such as inflammatory and immune responses. It is required for skin …

Antihyperglycemic activity of L-norvaline and L-arginine in high-fat diet and streptozotocin-treated male rats

H Javrushyan, E Nadiryan, A Grigoryan… - … and molecular pathology, 2022 - Elsevier
Background A decrease in nitric oxide (NO) bioavailability has been shown to cause
hyperglycemia, type II diabetes mellitus (DM), and chronic cardio-metabolic complications …

Atherosclerosis: Conventional intake of cardiovascular drugs versus delivery using nanotechnology–A new chance for causative therapy?

J Groner, A Goepferich, M Breunig - Journal of Controlled Release, 2021 - Elsevier
Atherosclerosis is the leading cause of death in developed countries. The pathogenetic
mechanism relies on a macrophage-based immune reaction to low density lipoprotein (LDL) …

Delivery of nitric oxide in the cardiovascular system: implications for clinical diagnosis and therapy

T Ma, Z Zhang, Y Chen, H Su, X Deng, X Liu… - International Journal of …, 2021 - mdpi.com
Nitric oxide (NO) is a key molecule in cardiovascular homeostasis and its abnormal delivery
is highly associated with the occurrence and development of cardiovascular disease (CVD) …