[HTML][HTML] Pathogenic mechanisms of post-acute sequelae of SARS-CoV-2 infection (PASC)

ZA Sherif, CR Gomez, TJ Connors, TJ Henrich… - Elife, 2023 - elifesciences.org
COVID-19, with persistent and new onset of symptoms such as fatigue, post-exertional
malaise, and cognitive dysfunction that last for months and impact everyday functioning, is …

[HTML][HTML] Pathogenesis underlying neurological manifestations of long COVID syndrome and potential therapeutics

A Leng, M Shah, SA Ahmad, L Premraj, K Wildi… - Cells, 2023 - mdpi.com
The development of long-term symptoms of coronavirus disease 2019 (COVID-19) more
than four weeks after primary infection, termed “long COVID” or post-acute sequela of …

[HTML][HTML] Postacute sequelae of COVID-19 at 2 years

B Bowe, Y Xie, Z Al-Aly - Nature medicine, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can lead to
postacute sequelae in multiple organ systems, but evidence is mostly limited to the first year …

[HTML][HTML] Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2

K Yin, MJ Peluso, X Luo, R Thomas, MG Shin… - Nature …, 2024 - nature.com
Long COVID (LC) occurs after at least 10% of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections, yet its etiology remains poorly understood. We used …

Effectiveness of COVID-19 treatment with nirmatrelvir–ritonavir or molnupiravir among US veterans: target trial emulation studies with one-month and six-month …

KL Bajema, K Berry, E Streja, N Rajeevan… - Annals of internal …, 2023 - acpjournals.org
Background: Information about the effectiveness of oral antivirals in preventing short-and
long-term COVID-19–related outcomes in the setting of Omicron variant transmission and …

[HTML][HTML] Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOVER initiative

H Bonilla, MJ Peluso, K Rodgers, JA Aberg… - Frontiers in …, 2023 - frontiersin.org
Although most individuals recover from acute SARS-CoV-2 infection, a significant number
continue to suffer from Post-Acute Sequelae of SARS-CoV-2 (PASC), including the …

Thromboinflammation in long COVID—the elusive key to postinfection sequelae?

L Nicolai, R Kaiser, K Stark - Journal of Thrombosis and Haemostasis, 2023 - Elsevier
Long COVID is a public health emergency affecting millions of people worldwide,
characterized by heterogeneous symptoms across multiple organ systems. Here, we discuss …

[HTML][HTML] Long-term outcomes following hospital admission for COVID-19 versus seasonal influenza: a cohort study

Y Xie, T Choi, Z Al-Aly - The Lancet Infectious Diseases, 2024 - thelancet.com
Background Previous comparative analyses of people admitted to hospital for COVID-19
versus influenza evaluated the risk of death, hospital readmission, and a narrow set of …

Mitigating neurological, cognitive, and psychiatric sequelae of COVID-19-related critical illness

P Pandharipande, SW Roberson… - The Lancet …, 2023 - thelancet.com
Despite advances in the treatment and mitigation of critical illness caused by infection with
SARS-CoV-2, millions of survivors have a devastating, post-acute infection syndrome known …

The coronavirus disease 2019 rebound study: a prospective cohort study to evaluate viral and symptom rebound differences in participants treated with nirmatrelvir …

JA Pandit, JM Radin, DC Chiang… - Clinical Infectious …, 2023 - academic.oup.com
Background The uptake of nirmatrelvir plus ritonavir (NPR) in patients with coronavirus
disease 2019 (COVID-19) has been limited by concerns around the rebound phenomenon …