Dynamic balance of pro‐and anti‐inflammatory signals controls disease and limits pathology

JM Cicchese, S Evans, C Hult, LR Joslyn… - Immunological …, 2018 - Wiley Online Library
Immune responses to pathogens are complex and not well understood in many diseases,
and this is especially true for infections by persistent pathogens. One mechanism that allows …

A new evidence-based optimal control in healthcare delivery: a better clinical treatment management for septic patients

Y Chen, K Bi, CHJ Wu, D Ben-Arieh - Computers & Industrial Engineering, 2019 - Elsevier
Abstract Treatment strategy of a realistic health care system must consider both system and
measurement errors. The traditional optimal control method is commonly applied to …

[PDF][PDF] Advances in numerical bifurcation software: MatCont

N Neirynck - 2019 - backoffice.biblio.ugent.be
The mathematical background of MatCont is bifurcation theory which is a field of hard
analysis, see in particular [60]. Bifurcation theory treats dynamical systems from a highlevel …

[HTML][HTML] A new method for optimizing sepsis therapy by nivolumab and meropenem combination: importance of early intervention and CTL reinvigoration rate as a …

A Gillis, A Ben Yaacov, Z Agur - Frontiers in Immunology, 2021 - frontiersin.org
Background: Recently, there has been a growing interest in applying immune checkpoint
blockers (ICBs), so far used to treat cancer, to patients with bacterial sepsis. We aimed to …

[图书][B] New algorithms for solving high-dimensional time-dependent optimal control problems and their applications in infectious disease models

Y Chen - 2022 - search.proquest.com
Infectious diseases have been the primary cause of human death worldwide nowadays. The
optimal control strategy for infectious disease has attracted increasing attention, becoming a …

[PDF][PDF] A bifurcation approach to bistability and stabilization in human visual perception

W Govaerts, YA Kuznetsov, HGE Meijer, N Neirynck… - 2020 - repository.ubn.ru.nl
We discuss a computational model that describes the stabilization of percept choices under
intermittent viewing of an ambiguous visual stimulus at long stimulus intervals (Toff). Unlike …