目的: 预测通关藤(marsdeniatenacissima, MT) 治疗非小细胞肺癌(non small cell
lungcancer, NSCLC) 的有效成分及分子作用机制. 方法: 通过国内外文献报道, 获取MT …

Apart from offering insight into the biomechanisms involved in cancer, many recent
mathematical modeling efforts aspire to the ultimate goal of clinical translation, wherein …

Background Contemporary biological observations have revealed a large variety of
mechanisms acting during the expansion of a tumor. However, there are still many …

Sea cucumber is a kind of food. Holothurian glycosaminoglycan (hGAG) is extracted from
the body wall of the sea cucumber. Administration of hGAG and cisplatin (DDP) together to …

Efficient use of Virtual Physiological Human (VPH)-type models for personalized treatment
response prediction purposes requires a precise model parameterization. In the case where …

Rapid advancements in high-throughput omics technologies and experimental protocols
have led to the generation of vast amounts of biomolecular data on cancer that now …

Part I of this thesis aims at developing an extensible and computationally efficient framework
for in silico modeling of tumor growth in a 3-dimensional, inhomogeneous and time-varying …

Objective The aim of the study was to evaluate the efficacy and safety of etoposide plus
thalidomide as maintenance therapy for elderly patients with advanced non-small cell lung …

In this work, we present the results of our study over the expected lifetime of the patients
diagnosed with relapsed squamous cell lung cancer, which is a subtype of non-small cell …

Περίληψη Στα πλαίσια της παρούσας διατριβής μελετήθηκαν οι επιστημονικοί τομείς της
Βιοπληροφορικής, της Υπολογιστικής Συστημικής Βιολογίας και της Μηχανικής Μάθησης με …