Microfluidic devices for drug delivery systems and drug screening

S Damiati, UB Kompella, SA Damiati, R Kodzius - Genes, 2018 - mdpi.com
Microfluidic devices present unique advantages for the development of efficient drug carrier
particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening …

[HTML][HTML] Towards principled design of cancer nanomedicine to accelerate clinical translation

M Souri, M Soltani, FM Kashkooli, MK Shahvandi… - Materials Today Bio, 2022 - Elsevier
Nanotechnology in medical applications, especially in oncology as drug delivery systems,
has recently shown promising results. However, although these advances have been …

Cancer nanomedicine: from targeted delivery to combination therapy

X Xu, W Ho, X Zhang, N Bertrand… - Trends in molecular …, 2015 - cell.com
The advent of nanomedicine marks an unparalleled opportunity to advance the treatment of
various diseases, including cancer. The unique properties of nanoparticles (NPs), such as …

[引用][C] Challenges and opportunities of nanomedicines in clinical translation

C Zheng, M Li, J Ding - Bio Integration, 2021 - Compuscript

Why microfluidics? Merits and trends in chemical synthesis

Y Liu, X Jiang - Lab on a Chip, 2017 - pubs.rsc.org
The intrinsic limitations of conventional batch synthesis have hindered its applications in
both solving classical problems and exploiting new frontiers. Microfluidic technology offers a …

Recent development of pH-responsive polymers for cancer nanomedicine

H Tang, W Zhao, J Yu, Y Li, C Zhao - Molecules, 2018 - mdpi.com
Cancer remains a leading cause of death worldwide with more than 10 million new cases
every year. Tumor-targeted nanomedicines have shown substantial improvements of the …

Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition

N Kong, W Tao, X Ling, J Wang, Y Xiao, S Shi… - Science Translational …, 2019 - science.org
Loss of function in tumor suppressor genes is commonly associated with the
onset/progression of cancer and treatment resistance. The p53 tumor suppressor gene, a …

Evolution and clinical translation of drug delivery nanomaterials

S Hassan, G Prakash, AB Ozturk, S Saghazadeh… - Nano today, 2017 - Elsevier
With the advent of technology, the role of nanomaterials in medicine has grown
exponentially in the last few decades. The main advantage of such materials has been …

Cancer‐targeting nanoparticles for combinatorial nucleic acid delivery

HJ Vaughan, JJ Green, SY Tzeng - Advanced Materials, 2020 - Wiley Online Library
Nucleic acids are a promising type of therapeutic for the treatment of a wide range of
conditions, including cancer, but they also pose many delivery challenges. For efficient and …

Microfluidic-assisted fabrication of carriers for controlled drug delivery

D Liu, H Zhang, F Fontana, JT Hirvonen, HA Santos - Lab on a Chip, 2017 - pubs.rsc.org
The microfluidic technique has brought unique opportunities toward the full control over the
production processes for drug delivery carriers, owing to the miniaturisation of the fluidic …