Bacteriophage (phage) T4 has served as an extraordinary model to elucidate biological structures and mechanisms. Recent discoveries on the T4 head (capsid) structure, portal …
Because vaccine development is a difficult process, this study reviews aspects of phages as vaccine delivery vehicles through a literature search. The results demonstrated that because …
Vaccination is one of the most successful measures in modern medicine to combat diseases, especially infectious diseases, and saves millions of lives every year. Vaccine …
T Yang, Y Chen, Y Xu, X Liu, M Yang, C Mao - Materials Science and …, 2023 - Elsevier
Viruses lacking the capacity to infect mammals exhibit minimal toxicity, good biocompatibility, and well-defined structures. As self-organized biomolecular assemblies …
Designing artificial viral vectors (AVVs) programmed with biomolecules that can enter human cells and carry out molecular repairs will have broad applications. Here, we describe …
VB Rao, J Zhu - Current opinion in virology, 2022 - Elsevier
The ability to deliver therapeutic genes and biomolecules into a human cell and restore a defective function has been the holy grail of medicine. Adeno-associated viruses and …
M Li, C Chen, X Wang, P Guo, H Feng, X Zhang… - Antiviral Research, 2023 - Elsevier
Vaccines that trigger mucosal immune responses at the entry portals of pathogens are highly desired. Here, we showed that antigen-decorated nanoparticle generated through …
H Zhong, Y Zhou, SY Mei, R Tang, JH Feng… - Frontiers in Public …, 2022 - frontiersin.org
Background The coronavirus disease 2019 (COVID-19) becomes a worldwide public health threat. Increasing evidence proves that COVID-19-induced acute injuries could be reversed …
H Brüssow - Microbial Biotechnology, 2023 - Wiley Online Library
Covid‐19 vaccines have within the first year prevented about 14 million deaths but did not induce a strong mucosal immune response. Data from US, UK, Singapore and Israel …