[HTML][HTML] Understanding bacteriophage tail fiber interaction with host surface receptor: the key “blueprint” for reprogramming phage host range

J Taslem Mourosi, A Awe, W Guo, H Batra… - International Journal of …, 2022 - mdpi.com
Bacteriophages (phages), as natural antibacterial agents, are being rediscovered because
of the growing threat of multi-and pan-drug-resistant bacterial pathogens globally. However …

[HTML][HTML] Bacteriophage T4 head: structure, assembly, and genome packaging

VB Rao, A Fokine, Q Fang, Q Shao - Viruses, 2023 - mdpi.com
Bacteriophage (phage) T4 has served as an extraordinary model to elucidate biological
structures and mechanisms. Recent discoveries on the T4 head (capsid) structure, portal …

[HTML][HTML] Aspects of phage-based vaccines for protein and epitope immunization

M Palma - Vaccines, 2023 - mdpi.com
Because vaccine development is a difficult process, this study reviews aspects of phages as
vaccine delivery vehicles through a literature search. The results demonstrated that because …

[HTML][HTML] Clinical perspective on topical vaccination strategies

P Popova, SP Chen, S Liao, M Sadarangani… - Advanced Drug Delivery …, 2024 - Elsevier
Vaccination is one of the most successful measures in modern medicine to combat
diseases, especially infectious diseases, and saves millions of lives every year. Vaccine …

Viruses as biomaterials

T Yang, Y Chen, Y Xu, X Liu, M Yang, C Mao - Materials Science and …, 2023 - Elsevier
Viruses lacking the capacity to infect mammals exhibit minimal toxicity, good
biocompatibility, and well-defined structures. As self-organized biomolecular assemblies …

[HTML][HTML] Design of bacteriophage T4-based artificial viral vectors for human genome remodeling

J Zhu, H Batra, N Ananthaswamy… - Nature …, 2023 - nature.com
Designing artificial viral vectors (AVVs) programmed with biomolecules that can enter
human cells and carry out molecular repairs will have broad applications. Here, we describe …

Bacteriophage T4 as a nanovehicle for delivery of genes and therapeutics into human cells

VB Rao, J Zhu - Current opinion in virology, 2022 - Elsevier
The ability to deliver therapeutic genes and biomolecules into a human cell and restore a
defective function has been the holy grail of medicine. Adeno-associated viruses and …

T4 bacteriophage nanoparticles engineered through CRISPR provide a versatile platform for rapid development of flu mucosal vaccines

M Li, C Chen, X Wang, P Guo, H Feng, X Zhang… - Antiviral Research, 2023 - Elsevier
Vaccines that trigger mucosal immune responses at the entry portals of pathogens are
highly desired. Here, we showed that antigen-decorated nanoparticle generated through …

[HTML][HTML] Scars of COVID-19: a bibliometric analysis of post-COVID-19 fibrosis

H Zhong, Y Zhou, SY Mei, R Tang, JH Feng… - Frontiers in Public …, 2022 - frontiersin.org
Background The coronavirus disease 2019 (COVID-19) becomes a worldwide public health
threat. Increasing evidence proves that COVID-19-induced acute injuries could be reversed …

Do we need nasal vaccines against COVID 19 to suppress the transmission of infections?

H Brüssow - Microbial Biotechnology, 2023 - Wiley Online Library
Covid‐19 vaccines have within the first year prevented about 14 million deaths but did not
induce a strong mucosal immune response. Data from US, UK, Singapore and Israel …