Malaria continued to be a deadly situation for the people of tropical and subtropical countries. Although there has been a marked reduction in new cases as well as mortality …
All organisms are defined by the makeup of their DNA. Over billions of years, the structure and information contained in that DNA, often referred to as genetic architecture, have been …
J Hassen, GS Alemayehu, H Dinka, L Golassa - Malaria Journal, 2022 - Springer
Background Plasmodium falciparum resistance to series of anti-malarial drugs is a major challenge in efforts to control and/or eliminate malaria globally. In 1998, following the …
S Chowdhary, Shalini, J Mosnier, I Fonta… - ACS Medicinal …, 2022 - ACS Publications
In the search of new antiplasmodial agents, a multitargeted approach was used in the synthesis of triazolopyrimidine-and 4-aminoquinolines-based hybrids. In vitro antiplasmodial …
Simple Summary Malaria is one of the most severe life-threatening human vector-borne diseases worldwide today, leading to high mortality. Children under the age of five and …
I Mushtaq, MS Sarwar, A Chaudhry… - Frontiers in Cellular …, 2024 - frontiersin.org
The escalating challenge of malaria control necessitates innovative approaches that extend beyond traditional control strategies. This review explores the incorporation of traditional …
DK Dosoo, JA Bailey, KP Asante, FB Oppong, K Niaré… - Plos one, 2022 - journals.plos.org
Intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine (IPTp- SP) is used to prevent malaria and associated unfavorable maternal and foetal outcomes in …
This study investigated the polymorphism in the P. falciparum chloroquine resistance transporter (pfcrt) gene 11 years after chloroquine (CQ) cessation in Jazan region …
W Okore, C Ouma, RO Okoth, R Yeda, LO Ingasia… - PLOS …, 2024 - journals.plos.org
Single nucleotide polymorphisms (SNPs) in the Plasmodium falciparum multi-drug resistance protein 1 (Pfmrp1) gene have previously been reported to confer resistance to …