NETosis and neutrophil extracellular traps in COVID-19: immunothrombosis and beyond

Y Zhu, X Chen, X Liu - Frontiers in Immunology, 2022 - frontiersin.org
Infection with SARS-CoV-2, the causative agent of the Coronavirus disease 2019 (COVID-
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …

The pathogenesis of coronavirus-19 disease

AC Borczuk, RK Yantiss - Journal of biomedical science, 2022 - Springer
Severe acute respiratory syndrome-associated coronavirus-2 (SARS-CoV-2) is the causal
agent of coronavirus disease-2019 (COVID-19), a systemic illness characterized by variably …

Locally organised and activated Fth1hi neutrophils aggravate inflammation of acute lung injury in an IL-10-dependent manner

K Wang, M Wang, X Liao, S Gao, J Hua, X Wu… - Nature …, 2022 - nature.com
Acute respiratory distress syndrome (ARDS) is a common respiratory critical syndrome with
no effective therapeutic intervention. Neutrophils function in the overwhelming inflammatory …

Neutrophil activation and neutrophil extracellular traps (NETs) in COVID‐19 ARDS and immunothrombosis

MC Cesta, M Zippoli, C Marsiglia… - European Journal of …, 2023 - Wiley Online Library
Acute respiratory distress syndrome (ARDS) is an acute inflammatory condition with a
dramatic increase in incidence since the beginning of the coronavirus disease 19 (COVID …

Neutrophils in COVID-19: recent insights and advances

J Li, K Zhang, ye Zhang, Z Gu, C Huang - Virology journal, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can lead to acute …

Role of neutrophils in acute viral infection

Y Ma, Y Zhang, L Zhu - Immunity, inflammation and disease, 2021 - Wiley Online Library
Neutrophils play multiple roles in acute viral infections. They restrict viral replication and
diffusion through phagocytosis, degranulation, respiratory burst, secretion of cytokines, and …

Neutrophil diversity in inflammation and cancer

S Carnevale, I Di Ceglie, G Grieco, A Rigatelli… - Frontiers in …, 2023 - frontiersin.org
Neutrophils are the most abundant circulating leukocytes in humans and the first immune
cells recruited at the site of inflammation. Classically perceived as short-lived effector cells …

Neutrophil extracellular traps and long COVID

A Shafqat, MH Omer, I Albalkhi… - Frontiers in …, 2023 - frontiersin.org
Post-acute COVID-19 sequelae, commonly known as long COVID, encompasses a range of
systemic symptoms experienced by a significant number of COVID-19 survivors. The …

Hallmarks of immune response in COVID-19: Exploring dysregulation and exhaustion

A Mazzoni, L Salvati, L Maggi, F Annunziato… - Seminars in …, 2021 - Elsevier
One and half year following the occurrence of COVID-19 pandemic, significant efforts from
laboratories all over the world generated a huge amount of data describing the prototypical …

Neutrophils predominate the immune signature of cerebral thrombi in COVID-19 stroke patients

A Genchi, A Semerano, G Schwarz… - Acta Neuropathologica …, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is associated with an increased risk of
thrombotic events. Ischemic stroke in COVID-19 patients entails high severity and mortality …