BackgroundMajor questions remain regarding the dysfunctional neural circuitry underlying
the pathophysiology of bipolar disorder (BD) in both youths and adults. In both age groups …

Aberrant regulation of synaptic function is thought to play a role in the aetiology of
psychiatric disorders, including schizophrenia and bipolar disorder. Normal neurotransmitter …

Pediatric bipolar disorder (PBD) is a severely debilitating illness, which is characterized by
episodes of mania and depression separated by periods of remission. Previous fMRI studies …

BackgroundThe hippocampus plays a central role in memory formation. There is
considerable evidence of abnormalities in hippocampal structure and function in …

BackgroundIndividuals with a history of bipolar disorder demonstrate abnormalities of
executive function, even during euthymia. The neural architecture underlying this and its …

Research into cognitive emotion regulation (ER) extends our understanding of human
cognition, which is capable of processing objective information and is crucial in maintaining …

Objective Emotion regulation deficits are a key characteristic of bipolar disorder (BD). In the
present study, we asked if deficits in emotion regulation are also a vulnerability marker for …

Objectives We combined multimodal functional magnetic resonance imaging (fMRI) and
structural magnetic resonance imaging to probe abnormalities in brain circuits underpinning …

Objectives Cognitive dysfunction affects a substantial proportion of patients with bipolar
disorder (BD), and genetic‐imaging paradigms may aid in the elucidation of mechanisms …

Objectives. Emotional dysregulation in bipolar disorder is thought to arise from dysfunction
within prefrontal cortical regions involved in cognitive control coupled with increased or …