[HTML][HTML] Gene–stress–epigenetic regulation of FKBP5: clinical and translational implications

AS Zannas, T Wiechmann, NC Gassen… - …, 2016 - nature.com
Stress responses and related outcomes vary markedly across individuals. Elucidating the
molecular underpinnings of this variability is of great relevance for developing individualized …

[PDF][PDF] Epigenetics of stress-related psychiatric disorders and gene× environment interactions

T Klengel, EB Binder - Neuron, 2015 - cell.com
A deeper understanding of the pathomechanisms leading to stress-related psychiatric
disorders is important for the development of more efficient preventive and therapeutic …

No support for historical candidate gene or candidate gene-by-interaction hypotheses for major depression across multiple large samples

R Border, EC Johnson, LM Evans… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Interest in candidate gene and candidate gene-by-environment interaction
hypotheses regarding major depressive disorder remains strong despite controversy …

The hidden efficacy of interventions: Gene× environment experiments from a differential susceptibility perspective

MJ Bakermans-Kranenburg… - Annual review of …, 2015 - annualreviews.org
The efficacy of interventions might be underestimated or even go undetected as a main
effect when it is hidden in gene-by-environment (G× E) interactions. This review moves …

[HTML][HTML] Testing the association of growth mindset and grades across a challenging transition: Is growth mindset associated with grades?

Y Li, TC Bates - Intelligence, 2020 - Elsevier
Mindset theory predicts that whether students believe basic ability is greatly malleable exerts
a major influence on their own educational attainment (Blackwell, Trzesniewski, & Dweck …

The levels problem in psychopathology

MI Eronen - Psychological medicine, 2021 - cambridge.org
Psychiatric disorders are studied at multiple levels, but there is no agreement on how these
levels are related to each other, or how they should be understood in the first place. In this …

Annual research review: discovery science strategies in studies of the pathophysiology of child and adolescent psychiatric disorders‐promises and limitations

Y Zhao, FX Castellanos - Journal of Child Psychology and …, 2016 - Wiley Online Library
Background Psychiatric science remains descriptive, with a categorical nosology intended to
enhance interobserver reliability. Increased awareness of the mismatch between categorical …

[HTML][HTML] Gene× environment interactions in schizophrenia: evidence from genetic mouse models

P Moran, J Stokes, J Marr, G Bock, L Desbonnet… - Neural …, 2016 - ncbi.nlm.nih.gov
The study of gene× environment, as well as epistatic interactions in schizophrenia, has
provided important insight into the complex etiopathologic basis of schizophrenia. It has also …

[HTML][HTML] Somatic comorbidity in children and adolescents with psychiatric disorders

S Agnafors, A Norman Kjellström, J Torgerson… - European Child & …, 2019 - Springer
In the adult population, psychiatric disorders are associated with somatic illness.
Explanatory life style factors have been found, but also a failure to recognize somatic illness …

[HTML][HTML] Air pollution exposure during pregnancy and childhood, APOE ε4 status and Alzheimer polygenic risk score, and brain structural morphology in …

E Essers, AC Binter, A Neumann, T White… - Environmental …, 2023 - Elsevier
Background Air pollution exposure is associated with impaired neurodevelopment, altered
structural brain morphology in children, and neurodegenerative disorders. Differential …