A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD)

J Peng, M Fan, C An, F Ni, W Huang… - Basic & clinical …, 2022 - Wiley Online Library
Cannabidiol (CBD) is an abundant non‐psychoactive phytocannabinoid in cannabis
extracts which has high affinity on a series of receptors, including Type 1 cannabinoid …

Cannabinoid receptor signaling in progenitor/stem cell proliferation and differentiation

I Galve-Roperh, V Chiurchiù, J Díaz-Alonso… - Progress in lipid …, 2013 - Elsevier
Cannabinoids, the active components of cannabis (Cannabis sativa) extracts, have attracted
the attention of human civilizations for centuries, much earlier than the discovery and …

The direct actions of cannabidiol and 2-arachidonoyl glycerol at GABAA receptors

T Bakas, PS Van Nieuwenhuijzen, SO Devenish… - Pharmacological …, 2017 - Elsevier
Cannabidiol (CBD) is a major non-intoxicating component of cannabis and possesses anti-
epileptic, anxiolytic and anti-hyperalgesic properties. The mechanism of action of CBD in …

[HTML][HTML] Lipids in psychiatric disorders and preventive medicine

M Schneider, B Levant, M Reichel, E Gulbins… - Neuroscience & …, 2017 - Elsevier
Psychiatric disorders like mood disorders, schizophrenia, or drug addiction affect a sizeable
proportion of the human population and severely compromise quality of life. Therefore …

Multi-target-directed ligands and other therapeutic strategies in the search of a real solution for Alzheimer's disease

A Agis-Torres, M Sollhuber… - Current …, 2014 - ingentaconnect.com
The lack of an adequate therapy for Alzheimer's Disease (AD) contributes greatly to the
continuous growing amount of papers and reviews, reflecting the important efforts made by …

Epigenetic effects of cannabis exposure

H Szutorisz, YL Hurd - Biological psychiatry, 2016 - Elsevier
The past decade has witnessed a number of societal and political changes that have raised
critical questions about the long-term impact of marijuana (Cannabis sativa) that are …

The critical role of CCK in the regulation of food intake and diet-induced obesity

CR Cawthon, CB de La Serre - Peptides, 2021 - Elsevier
Abstract In 1973, Gibbs, Young, and Smith showed that exogenous cholecystokinin (CCK)
administration reduces food intake in rats. This initial report has led to thousands of studies …

Brain activity of anandamide: a rewarding bliss?

M Scherma, P Masia, V Satta, W Fratta… - Acta Pharmacologica …, 2019 - nature.com
Anandamide is a lipid mediator that acts as an endogenous ligand of CB1 receptors. These
receptors are also the primary molecular target responsible for the pharmacological effects …

Some prospective alternatives for treating pain: the endocannabinoid system and its putative receptors GPR18 and GPR55

R Guerrero-Alba, P Barragán-Iglesias… - Frontiers in …, 2019 - frontiersin.org
Background: Marijuana extracts (cannabinoids) have been used for several millennia for
pain treatment. Regarding the site of action, cannabinoids are highly promiscuous …

Cannabinoid exposure during pregnancy and its impact on immune function

C Dong, J Chen, A Harrington, KY Vinod… - Cellular and Molecular …, 2019 - Springer
Cannabinoids are the most commonly abused illicit drugs worldwide. While cannabis can be
beneficial for certain heath conditions, abuse of potent synthetic cannabinoids has been on …