The extracellular matrix regulates tissue development and homeostasis, and its
dysregulation contributes to neoplastic progression. The extracellular matrix serves not only …

Completion of genome sequences for many organisms allows a reasonably complete
definition of the complement of extracellular matrix (ECM) proteins. In mammals this “core …

Simple Summary The formation of new blood vessels from already existing ones is a
process of high clinical relevance, since it is of great importance for both physiological and …

ABSTRACT The α1β1, α2β1, α10β1 and α11β1 integrins constitute a subset of the integrin
family with affinity for GFOGER-like sequences in collagens. Integrins α1β1 and α2β1 were …

The extracellular matrix (ECM) consists of numerous macromolecules classified traditionally
into collagens, elastin, and microfibrillar proteins, proteoglycans including hyaluronan, and …

We show that endothelial cell (EC)–generated vascular guidance tunnels (ie, matrix spaces
created during tube formation) serve as conduits for the recruitment and motility of pericytes …

Data on gastroenteropancreatic neuroendocrine neoplasms (NEN) G3 (well-differentiated
neuroendocrine tumors (NET G3) and neuroendocrine carcinoma (NEC)) are limited. We …

Extracellular matrix (ECM) is essential for all stages of angiogenesis. In the adult,
angiogenesis begins with endothelial cell (EC) activation, degradation of vascular basement …

The extracellular matrix (ECM) is a complex network of proteins, glycoproteins,
proteoglycans, and polysaccharides. Through multiple interactions with each other and the …

Heterotrimers composed of collagen type IV alpha 1 (COL4A1) and alpha 2 (COL4A2)
constitute one of the most abundant components of nearly all basement membranes …