Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Protein posttranslational modifications (PTMs) refer to the breaking or generation of covalent
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …

A characteristic feature of COVID‐19, the disease caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) infection, is the dysregulated immune response …

The signaling adaptor MAVS forms prion-like aggregates to activate the innate antiviral
immune response after viral infection. However, spontaneous aggregation of MAVS can …

To effectively protect the host from viral infection while avoiding excessive
immunopathology, the innate immune response must be tightly controlled. However, the …

The G protein-coupled receptor ADGRE5 (CD97) binds to various metabolites that play
crucial regulatory roles in metabolism. However, its function in the antiviral innate immune …

RNA virus infection usually triggers a range of host immune responses, including the
induction of proinflammatory cytokines, interferons, and interferon-stimulated genes (ISGs) …

Abstract Interferon-tau (IFNT), a pregnancy recognition signal in ruminants, promotes the
establishment of endometrial receptivity by inducing the expression of interferon-stimulated …

The adaptor molecule MAVS forms prion-like aggregates to govern the RIG-I-like receptor
(RLR) signaling cascade. Lys63 (K63)-linked polyubiquitination is critical for MAVS …

P-Hydroxylcinnamaldehyde (CMSP) was firstly isolated from Chinese medicine
Cochinchinnamomordica seed (CMS) by our team and has been verified to have growth …