Over the years, my colleagues and I have come to realise that the likelihood of pharmaceutical drugs being able to diffuse through whatever unhindered phospholipid …
Y Zhou, L Nevosadová, E Eliasson, VM Lauschke - Human genomics, 2023 - Springer
Background Genetic variability in the cytochrome P450 CYP2C9 constitutes an important predictor for efficacy and safety of various commonly prescribed drugs, including coumarin …
Background To date, research on adverse drug reactions (ADRs) has focused on secondary care, and there is a paucity of studies that have prospectively examined ADRs affecting …
Background Adverse drug reactions (ADRs) have continued to be a public health challenge with significant clinical and healthcare costs. However, little is known regarding the …
JM Serra López-Matencio, M Gómez… - Pharmaceuticals, 2021 - mdpi.com
The discovery of antifibrotic agents have resulted in advances in the therapeutic management of idiopathic pulmonary fibrosis (IPF). Currently, nintedanib and pirfenidone …
Recent medical advancements have increased life expectancy, leading to a surge in patients affected by multiple chronic diseases and consequent polypharmacy, especially …
MT Eadon, MB Rosenman, P Zhang… - The …, 2023 - nature.com
Adverse drug events (ADEs) account for a significant mortality, morbidity, and cost burden. Pharmacogenetic testing has the potential to reduce ADEs and inefficacy. The objective of …
Aim This study aimed to reveal the current status of the literature on rational prescribing training in undergraduate medical education. Methods This study followed the preferred …
M Polaczyk, A Olszanecka… - Polish Heart …, 2022 - journals.viamedica.pl
Background: Women have been underrepresented in large clinical trials in hypertension, and the incidence of adverse drug reactions by sex has been not sufficiently described …