[HTML][HTML] Scutellaria baicalensis Georgi and Their Natural Flavonoid Compounds in the Treatment of Ovarian Cancer: A Review

J Cai, Q Hu, Z He, X Chen, J Wang, X Yin, X Ma, J Zeng - Molecules, 2023 - mdpi.com
Ovarian cancer (OC) is one of the most common types of cancer in women with a high
mortality rate, and the treatment of OC is prone to high recurrence rates and side effects …

[HTML][HTML] Natural compounds as lactate dehydrogenase inhibitors: Potential therapeutics for lactate dehydrogenase inhibitors-related diseases

JH Han, EJ Lee, W Park, KT Ha… - Frontiers in …, 2023 - frontiersin.org
Lactate dehydrogenase (LDH) is a crucial enzyme involved in energy metabolism and
present in various cells throughout the body. Its diverse physiological functions encompass …

[HTML][HTML] Natural flavones from edible and medicinal plants exhibit enormous potential to treat ulcerative colitis

Q Lu, Y Xie, J Luo, Q Gong, C Li - Frontiers in Pharmacology, 2023 - frontiersin.org
Ulcerative colitis (UC) is a chronic aspecific gut inflammatory disorder that primarily involves
the recta and colons. It mostly presents as a long course of repeated attacks. This disease …

[HTML][HTML] Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway

Y Sun, J Weng, X Chen, S Ma, Y Zhang, F Zhang… - Biomedicine & …, 2023 - Elsevier
In recent study, the pathological mechanism of liver fibrosis has been associated with
hepatic stellate cell (HSC) senescence. Targeted induction of HSC senescence is …

Oroxylin a promoted apoptotic extracellular vesicles transfer of glycolytic kinases to remodel immune microenvironment in hepatocellular carcinoma model

P Wang, J Cao, Z Feng, Y Tang, X Han, T Mao… - European Journal of …, 2023 - Elsevier
Although oroxylin A, a natural flavonoid compound, suppressed progression of
hepatocellular carcinoma, whether the tumor microenvironment especially the …

[HTML][HTML] The role of natural flavonoids as telomerase inhibitors in suppressing Cancer Growth

N Parekh, A Garg, R Choudhary, M Gupta, G Kaur… - Pharmaceuticals, 2023 - mdpi.com
Cancer is a complex and multifaceted group of diseases characterized by the uncontrolled
growth and spread of abnormal cells. While cancer can be challenging and life-altering …

[HTML][HTML] Skullcapflavone II, a novel NQO1 inhibitor, alleviates aristolochic acid I-induced liver and kidney injury in mice

Y Dong, S Chen, H He, Z Sun, L Jiang, Y Gu… - Acta Pharmacologica …, 2023 - nature.com
Aristolochic acid I (AAI) is a well established nephrotoxin and human carcinogen. Cytosolic
NAD (P) H quinone oxidoreductase 1 (NQO1) plays an important role in the nitro reduction …

[HTML][HTML] Delineating the role of nuclear receptors in colorectal cancer, a focused review

MK Manickasamy, S Jayaprakash, S Girisa, A Kumar… - Discover Oncology, 2024 - Springer
Colorectal cancer (CRC) stands as one of the most prevalent form of cancer globally,
causing a significant number of deaths, surpassing 0.9 million in the year 2020. According to …

[HTML][HTML] An Updated Review of Chinese Skullcap (Scutellaria baicalensis): Emphasis on Phytochemical Constituents and Pharmacological Attributes

DK Chanchal, K Singh, B Bhushan… - Pharmacological …, 2023 - Elsevier
Abstract Chinese Skullcap (Scutellaria baicalensis) is a traditional medicinal herb with a rich
history of use in Traditional Chinese Medicine (TCM). This review aims to provide an …

[HTML][HTML] Exploring the nexus of nuclear receptors in hematological malignancies

MK Manickasamy, A Sajeev… - Cellular and Molecular …, 2024 - Springer
Hematological malignancies (HM) represent a subset of neoplasms affecting the blood,
bone marrow, and lymphatic systems, categorized primarily into leukemia, lymphoma, and …