The amyloid cascade hypothesis: an updated critical review

KP Kepp, NK Robakis, PF Høilund-Carlsen, SL Sensi… - Brain, 2023 - academic.oup.com
Results from recent clinical trials of antibodies that target amyloid-β (Aβ) for Alzheimer's
disease have created excitement and have been heralded as corroboration of the amyloid …

[HTML][HTML] Guts imbalance imbalances the brain: a review of gut microbiota association with neurological and psychiatric disorders

L Mitrea, SA Nemeş, K Szabo, BE Teleky… - Frontiers in …, 2022 - frontiersin.org
In the last ten years, there has been a growing interest regarding the relationship between
gut microbiota, brain, and neurological-associated affections. As multiple preclinical and …

Effects of physical activity and exercise on the cognitive function of patients with Alzheimer disease: a meta-analysis

R Jia, J Liang, Y Xu, Y Wang - BMC geriatrics, 2019 - Springer
Background Alzheimer's disease (AD), as the most common cause of dementia, brings huge
economic burden for patients and social health care systems, which motivates researchers …

[HTML][HTML] The biological pathways of Alzheimer disease: A review

M Calabrò, C Rinaldi, G Santoro, C Crisafulli - AIMS neuroscience, 2021 - ncbi.nlm.nih.gov
Alzheimer disease is a progressive neurodegenerative disorder, mainly affecting older
people, which severely impairs patients' quality of life. In the recent years, the number of …

Preclinical Alzheimer's disease: definition, natural history, and diagnostic criteria

B Dubois, H Hampel, HH Feldman, P Scheltens… - Alzheimer's & …, 2016 - Elsevier
During the past decade, a conceptual shift occurred in the field of Alzheimer's disease (AD)
considering the disease as a continuum. Thanks to evolving biomarker research and …

[HTML][HTML] Ketogenic diet in Alzheimer's disease

M Rusek, R Pluta, M Ułamek-Kozioł… - International journal of …, 2019 - mdpi.com
At present, the prevalence of Alzheimer's disease, a devastating neurodegenerative
disorder, is increasing. Although the mechanism of the underlying pathology is not fully …

Effects of vitamin D supplementation on cognitive function and blood Aβ-related biomarkers in older adults with Alzheimer's disease: a randomised, double-blind …

J Jia, J Hu, X Huo, R Miao, Y Zhang… - Journal of Neurology …, 2019 - jnnp.bmj.com
Objective Our study aimed to assess the effect of a 12-month vitamin D supplementation on
cognitive function and amyloid beta (Aβ)-related biomarkers in subjects with Alzheimer's …

Dietary recommendations for the prevention of depression

RS Opie, C Itsiopoulos, N Parletta… - Nutritional …, 2017 - Taylor & Francis
Background: Major depressive disorder is a common, chronic condition that imposes a
substantial burden of disability globally. As current treatments are estimated to address only …

Current research therapeutic strategies for Alzheimer's disease treatment

J Folch, D Petrov, M Ettcheto, S Abad… - Neural …, 2016 - Wiley Online Library
Alzheimer's disease (AD) currently presents one of the biggest healthcare issues in the
developed countries. There is no effective treatment capable of slowing down disease …

Brain health: the importance of recognizing cognitive impairment: an IAGG consensus conference

JE Morley, JC Morris, M Berg-Weger, S Borson… - Journal of the American …, 2015 - Elsevier
Cognitive impairment creates significant challenges for patients, their families and friends,
and clinicians who provide their health care. Early recognition allows for diagnosis and …