Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

H Sies, VV Belousov, NS Chandel, MJ Davies… - … reviews Molecular cell …, 2022 - nature.com
Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

Oxidative stress in human pathology and aging: molecular mechanisms and perspectives

YA Hajam, R Rani, SY Ganie, TA Sheikh, D Javaid… - Cells, 2022 - mdpi.com
Reactive oxygen and nitrogen species (RONS) are generated through various endogenous
and exogenous processes; however, they are neutralized by enzymatic and non-enzymatic …

The chemistry of reactive oxygen species (ROS) revisited: outlining their role in biological macromolecules (DNA, lipids and proteins) and induced pathologies

CA Juan, JM Pérez de la Lastra, FJ Plou… - International journal of …, 2021 - mdpi.com
Living species are continuously subjected to all extrinsic forms of reactive oxidants and
others that are produced endogenously. There is extensive literature on the generation and …

[HTML][HTML] Cellular Red-Ox system in health and disease: The latest update

AB Jena, RR Samal, NK Bhol, AK Duttaroy - Biomedicine & …, 2023 - Elsevier
Cells are continually exposed to reactive oxygen species (ROS) generated during cellular
metabolism. Apoptosis, necrosis, and autophagy are biological processes involving a …

Role of copper on mitochondrial function and metabolism

LM Ruiz, A Libedinsky, AA Elorza - Frontiers in molecular biosciences, 2021 - frontiersin.org
Copper is essential for life processes like energy metabolism, reactive oxygen species
detoxification, iron uptake, and signaling in eukaryotic organisms. Mitochondria gather …

[HTML][HTML] Beneficial and detrimental effects of reactive oxygen species on lifespan: a comprehensive review of comparative and experimental studies

HJ Shields, A Traa, JM Van Raamsdonk - Frontiers in cell and …, 2021 - frontiersin.org
Aging is the greatest risk factor for a multitude of diseases including cardiovascular disease,
neurodegeneration and cancer. Despite decades of research dedicated to understanding …

Mitochondrial oxidative stress in the tumor microenvironment and cancer immunoescape: foe or friend?

CL Kuo, A Ponneri Babuharisankar, YC Lin… - Journal of biomedical …, 2022 - Springer
The major concept of" oxidative stress" is an excess elevated level of reactive oxygen
species (ROS) which are generated from vigorous metabolism and consumption of oxygen …

The emerging role of microplastics in systemic toxicity: Involvement of reactive oxygen species (ROS)

A Das - Science of The Total Environment, 2023 - Elsevier
Plastic pollution is one of the most pressing environmental threats the world is facing
currently. The degradation of macroplastics into smaller forms viz. microplastics (MPs) or …

ROS homeostasis in abiotic stress tolerance in plants

KK Nadarajah - International journal of molecular sciences, 2020 - mdpi.com
Climate change-induced abiotic stress results in crop yield and production losses. These
stresses result in changes at the physiological and molecular level that affect the …

Gut microbiota and complications of type-2 diabetes

CO Iatcu, A Steen, M Covasa - Nutrients, 2021 - mdpi.com
The gut microbiota has been linked to the emergence of obesity, metabolic syndrome and
the onset of type 2 diabetes through decreased glucose tolerance and insulin resistance …