Role of gut microbiome in autism spectrum disorder and its therapeutic regulation

MA Taniya, HJ Chung, A Al Mamun, S Alam… - Frontiers in cellular …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a neurological disorder that affects normal brain
development. The recent finding of the microbiota–gut–brain axis indicates the bidirectional …

Oxidative stress in autism spectrum disorder

G Bjørklund, NA Meguid, MA El-Bana, AA Tinkov… - Molecular …, 2020 - Springer
Abstract According to the United States Centers for Disease Control and Prevention (CDC),
as of July 11, 2016, the reported average incidence of children diagnosed with an autism …

The human gut microbiome as a potential factor in autism spectrum disorder

A Alharthi, S Alhazmi, N Alburae… - International journal of …, 2022 - mdpi.com
The high prevalence of gastrointestinal (GI) disorders among autism spectrum disorder
(ASD) patients has prompted scientists to look into the gut microbiota as a putative trigger in …

Altering the gut microbiome to potentially modulate behavioral manifestations in autism spectrum disorders: A systematic review

C Davies, D Mishra, RS Eshraghi, J Mittal… - Neuroscience & …, 2021 - Elsevier
There is a potential association between gastrointestinal (GI) symptoms and the severity of
autism spectrum disorder (ASD). Given this correlation, the possible impact of probiotics and …

Prenatal valproate in rodents as a tool to understand the neural underpinnings of social dysfunctions in autism spectrum disorder

AM Tartaglione, S Schiavi, G Calamandrei, V Trezza - Neuropharmacology, 2019 - Elsevier
Impairments in social interaction and verbal and non verbal communication are among the
main features of Autism Spectrum Disorder (ASD). The causes of ASD are still unknown but …

Imbalance in pro-inflammatory and anti-inflammatory cytokines milieu in B cells of children with autism

A Nadeem, SF Ahmad, NO Al-Harbi, LY Al-Ayadhi… - Molecular …, 2022 - Elsevier
B cells play multiple roles in preservation of healthy immune system including management
of immune responses by expression of pro-and anti-inflammatory cytokines. Several earlier …

Mapping of the benzoate metabolism by human gut microbiome indicates food-derived metagenome evolution

M Yadav, A Lomash, S Kapoor, R Pandey… - Scientific reports, 2021 - nature.com
Sodium benzoate is one of the widely used food preservatives and its metabolism in the
human body has been studied only with the host perspective. Despite the human gut …

Gut-induced inflammation during development may compromise the blood-brain barrier and predispose to autism spectrum disorder

RS Eshraghi, C Davies, R Iyengar, L Perez… - Journal of clinical …, 2020 - mdpi.com
Recently, the gut microbiome has gained considerable interest as one of the major
contributors to the pathogenesis of multi-system inflammatory disorders. Several studies …

Gut microbiome-mediated epigenetic regulation of brain disorder and application of machine learning for multi-omics data analysis

H Kaur, Y Singh, S Singh, RB Singh - Genome, 2021 - cdnsciencepub.com
The gut–brain axis (GBA) is a biochemical link that connects the central nervous system
(CNS) and enteric nervous system (ENS). Clinical and experimental evidence suggests gut …

Could Candida Overgrowth Be Involved in the Pathophysiology of Autism?

A Herman, AP Herman - Journal of Clinical Medicine, 2022 - mdpi.com
The purpose of this review is to summarize the current acquiredknowledge of Candida
overgrowth in the intestine as a possible etiology of autism spectrum disorder (ASD). The …