Traumatic injury to peripheral nerves results in the loss of neural functions. Recovery by
regeneration depends on the cellular and molecular events of Wallerian degeneration that …

In this article we first discuss the factors that regulate macrophage recruitment, activation,
and myelin phagocytosis during Wallerian degeneration and some of the factors involved in …

Abstract Treatment of neuropathic pain, triggered by multiple insults to the nervous system,
is a clinical challenge because the underlying mechanisms of neuropathic pain …

Peripheral nerves regenerate following injury due to the effective activation of the intrinsic
growth capacity of the neurons and the formation of a permissive pathway for outgrowth due …

In contrast to physiological pain, pathological pain is not dependent on the presence of
tissue‐damaging stimuli. One type of pathological pain—neuropathic pain—is often a …

The nervous system detects and interprets a variety of chemical, mechanical, and thermal
stimuli. In the face of tissue injury, local inflammatory products perpetuate ongoing activity …

This review will focus on matrix metalloproteinases (MMPs) and their inhibitors in the context
of spinal cord injury (SCI). MMPs have a specific cellular and temporal pattern of expression …

Neuropathic pain affects millions of people globally and could be a disease on its own right.
Current treatments focus on blocking neurotransmission and have resulted in limited …

The peripheral nervous system (PNS) exhibits a much larger capacity for regeneration than
the central nervous system (CNS). One reason for this difference is the difference in glial cell …

Neuropathic pain has been described as the “most terrible of all tortures which a nerve
wound may inflict” and arises as a consequence of nerve injury either of the peripheral or …