[PDF][PDF] Meta-hallmarks of aging and cancer

C López-Otín, F Pietrocola, D Roiz-Valle, L Galluzzi… - Cell metabolism, 2023 - cell.com
Both aging and cancer are characterized by a series of partially overlapping" hallmarks" that
we subject here to a meta-analysis. Several hallmarks of aging (ie, genomic instability …

[HTML][HTML] Epigenetic regulation of aging: implications for interventions of aging and diseases

K Wang, H Liu, Q Hu, L Wang, J Liu, Z Zheng… - Signal transduction and …, 2022 - nature.com
Aging is accompanied by the decline of organismal functions and a series of prominent
hallmarks, including genetic and epigenetic alterations. These aging-associated epigenetic …

Mitochondrial dysfunction in aging

Y Guo, T Guan, K Shafiq, Q Yu, X Jiao, D Na… - Ageing Research …, 2023 - Elsevier
Aging is a complex process that features a functional decline in many organelles. Although
mitochondrial dysfunction is suggested as one of the determining factors of aging, the role of …

[HTML][HTML] Animal-and plant-based protein sources: a scoping review of human health outcomes and environmental impact

L Ferrari, SA Panaite, A Bertazzo, F Visioli - Nutrients, 2022 - mdpi.com
Dietary proteins are indispensable to human nutrition. In addition to their tissue-building
function, they affect body composition and regulate various metabolic pathways, as well as …

[HTML][HTML] Phytochemicals and biological activities of walnut septum: A systematic review

L Mateș, ME Rusu, DS Popa - Antioxidants, 2023 - mdpi.com
In the last few decades, scientific evidence has stressed the importance of plants in the
prevention and/or supportive treatment of a plethora of diseases, many of them chronic, age …

[HTML][HTML] Aging conundrum: A perspective for ovarian aging

J Wu, Y Liu, Y Song, L Wang, J Ai, K Li - Frontiers in Endocrinology, 2022 - frontiersin.org
Progressive loss of physiological integrity and accumulation of degenerative changes
leading to functional impairment and increased susceptibility to diseases are the main …

[HTML][HTML] Branched-chain amino acids and insulin resistance, from protein supply to diet-induced obesity

JP De Bandt, X Coumoul, R Barouki - Nutrients, 2022 - mdpi.com
For more than a decade, there has been a wide debate about the branched-chain amino
acids (BCAA) leucine, valine, and isoleucine, with, on the one hand, the supporters of their …

[HTML][HTML] Nutrition strategies promoting healthy aging: From improvement of cardiovascular and brain health to prevention of age-associated diseases

M Fekete, Z Szarvas, V Fazekas-Pongor, A Feher… - Nutrients, 2022 - mdpi.com
Background: An increasing number of studies suggest that diet plays an important role in
regulating aging processes and modulates the development of the most important age …

Healthy lifestyle behaviors and biological aging in the US National Health and Nutrition Examination Surveys 1999–2018

A Thomas, DW Belsky, Y Gu - The Journals of Gerontology …, 2023 - academic.oup.com
People who have a balanced diet and engage in more physical activity live longer, healthier
lives. This study aimed to test the hypothesis that these associations reflect a slowing of …

[HTML][HTML] The effects of dietary interventions on brain aging and neurological diseases

F Lobo, J Haase, S Brandhorst - Nutrients, 2022 - mdpi.com
Dietary interventions can ameliorate age-related neurological decline. Decades of research
of in vitro studies, animal models, and clinical trials support their ability and efficacy to …