Abstract Since ancient times, Polygonatum Mill.(Asparagaceae) has been utilized as a
medicinal and culinary resource in China. Its efficacy in treating various illnesses has been …

DNA damage‐induced senescence is initially sustained by p53. Senescent cells produce a
senescence‐associated secretory phenotype (SASP) that impacts the aging …

Vascular dementia (VaD) is the second most common type of dementia. VaD is synonymous
with ageing, and its symptoms place a significant burden on the health and wellbeing of …

Although prior research has synthesized the relationships between the Mediterranean diet
(MD) and components of physical fitness (PF) in adults, they are limited and inconclusive …

Shortly after the discovery of Klotho, interest grew in its potential role in chronic kidney
disease (CKD). There are three isoforms of the Klotho protein: αKlotho, βKlotho and γKlotho …

Perfluorobutane sulfonates (PFBS) have garnered extensive utilization because of their
distinctive physicochemical properties. The liver acts as a key target organ for toxicity within …

Dietary composition substantially determines human health and affects complex diseases,
including obesity, inflammation and cancer. Thus, food supplements have been widely used …

Background Arachidonic acid (AA), one of the most ubiquitous polyunsaturated fatty acids
(PUFAs), provides fluidity to mammalian cell membranes. It is derived from linoleic acid (LA) …

Calorie restriction (CR) typically promotes a reduction in body mass, which correlates with
increased lifespan. We evaluated the overall changes in survival, body mass dynamics, and …

Caloric restriction is an effective means of extending a healthy lifespan. Fasting mimicking
diet (FMD) is a growing pattern of caloric restriction. We found that FMD significantly …