Long COVID: molecular mechanisms and detection techniques
A Constantinescu-Bercu, A Lobiuc… - International Journal of …, 2023 - mdpi.com
Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC), has
emerged as a significant health concern following the COVID-19 pandemic. Molecular …
emerged as a significant health concern following the COVID-19 pandemic. Molecular …
α1-Adrenergic Receptors: Insights into Potential Therapeutic Opportunities for COVID-19, Heart Failure, and Alzheimer's Disease
DM Perez - International journal of molecular sciences, 2023 - mdpi.com
α1-Adrenergic receptors (ARs) are members of the G-Protein Coupled Receptor superfamily
and with other related receptors (β and α2), they are involved in regulating the sympathetic …
and with other related receptors (β and α2), they are involved in regulating the sympathetic …
[HTML][HTML] Warmer ambient air temperatures reduce nasal turbinate and brain infection, but increase lung inflammation in the K18-hACE2 mouse model of COVID-19
Warmer climatic conditions have been associated with fewer COVID-19 cases. Herein we
infected K18-hACE2 mice housed at the standard animal house temperature of∼ 22° C, or …
infected K18-hACE2 mice housed at the standard animal house temperature of∼ 22° C, or …
Deciphering the host genetic factors conferring susceptibility to severe COVID-19 using exome sequencing
The COVID-19 pandemic remains a significant public health concern despite the new
vaccines and therapeutics. The clinical course of acute SARS-CoV-2 infection is highly …
vaccines and therapeutics. The clinical course of acute SARS-CoV-2 infection is highly …
Host genetic determinants of COVID‐19 susceptibility and severity: A systematic review and meta‐analysis
S Eshetie, P Jullian, B Benyamin… - Reviews in Medical …, 2023 - Wiley Online Library
Genome‐wide association studies (GWASs) have identified single nucleotide
polymorphisms (SNPs) associated with susceptibility and severity of coronavirus disease …
polymorphisms (SNPs) associated with susceptibility and severity of coronavirus disease …
Host genetic variants associated with COVID-19 reconsidered in a Slovak cohort
M Skerenova, M Cibulka, Z Dankova… - Advances in Medical …, 2024 - Elsevier
We present the results of an association study involving hospitalized coronavirus disease
2019 (COVID-19) patients with a clinical background during the 3rd pandemic wave of …
2019 (COVID-19) patients with a clinical background during the 3rd pandemic wave of …
[HTML][HTML] Genetic signature detected in T cell receptors from patients with severe COVID-19
Characterization of host genetic factors contributing to COVID-19 severity promises
advances on drug discovery to fight the disease. Most genetic analyses to date have …
advances on drug discovery to fight the disease. Most genetic analyses to date have …
[HTML][HTML] Association of human leukocyte antigen class I and class II alleles and haplotypes in COVID-19 infection in a western Indian population
AS Tripathy, P Wagh, S Vishwakarma… - Infection, Genetics …, 2023 - ncbi.nlm.nih.gov
In December 2022 an interesting and potentially important review article published in this
journal entitled “Genome-wide association studies of COVID-19: Connecting the dots” …
journal entitled “Genome-wide association studies of COVID-19: Connecting the dots” …
TAS2R38 haplotypes, COVID-19 infection, and symptomatology: a cross-sectional analysis of data from the Canadian Longitudinal Study on Aging
T Meng, DE Nielsen - Scientific Reports, 2024 - nature.com
The TAS2R38 gene is well known for its function in bitter taste sensitivity, but evidence also
suggests a role in innate immunity. TAS2R38 may be relevant in coronavirus disease 2019 …
suggests a role in innate immunity. TAS2R38 may be relevant in coronavirus disease 2019 …
In silico evidence that substitution of glycine for valine (p. G8V) in a common variant of TMPRSS2 isoform 1 increases accessibility to an endocytic signal: Implication …
M Calcagnile, F Damiano, G Lobreglio, L Siculella… - Biochimie, 2024 - Elsevier
The TMPRSS2 protease plays a key role in the entry of the SARS-CoV-2 into cells. The
TMPRSS2 gene is highly polymorphic in humans, and some polymorphisms may affect the …
TMPRSS2 gene is highly polymorphic in humans, and some polymorphisms may affect the …