Neuroimaging and epigenetic analysis reveal novel epigenetic loci in major depressive disorder
BackgroundEpigenetic modifications, such as DNA methylation, contribute to the
pathophysiology of major depressive disorder (MDD). This study aimed to identify novel …
pathophysiology of major depressive disorder (MDD). This study aimed to identify novel …
Comparative analysis of the nucleus accumbens transcriptional features in multiple depressive animal models
Y Yu, X Li, T Teng, Y He, Y Jiang, X Liu, X Zhou… - Behavioural Brain …, 2024 - Elsevier
Chronic stress is deemed a significant clinical contributor to depression. The use of animal
models of chronic stress can fully reveal the complex pathological mechanisms and their …
models of chronic stress can fully reveal the complex pathological mechanisms and their …
Major Depressive Disorder Trait Genes Promote Triple-Negative Breast Cancer Progression and Predict Immunotherapy Responses
Z Zhuo, W Lu, D Zhang, Y Cui, X Wu, H Mei, L Chang… - 2023 - researchsquare.com
TNBC is the most malignant subtype of breast cancer and there are no accurate and
effective therapeutic targets. Immunotherapy is a promising approach for the treatment of …
effective therapeutic targets. Immunotherapy is a promising approach for the treatment of …