[HTML][HTML] Homotopic functional connectivity disruptions in schizophrenia and their associated gene expression

M Cai, Y Ji, Q Zhao, H Xue, Z Sun, H Wang, Y Zhang… - Neuroimage, 2024 - Elsevier
It has been revealed that abnormal voxel-mirrored homotopic connectivity (VMHC) is
present in patients with schizophrenia, yet there are inconsistencies in the relevant findings …

Multi-centre analysis of networks and genes modulated by hypothalamic stimulation in patients with aggressive behaviours

FV Gouveia, J Germann, GJB Elias, A Boutet, A Loh… - Elife, 2023 - elifesciences.org
Deep brain stimulation targeting the posterior hypothalamus (pHyp-DBS) is being
investigated as a treatment for refractory aggressive behavior, but its mechanisms of action …

[HTML][HTML] Spatial transcriptomic patterns underlying amyloid-β and tau pathology are associated with cognitive dysfunction in Alzheimer's disease

M Yu, SL Risacher, KT Nho, Q Wen, AL Oblak… - Cell reports, 2024 - cell.com
Amyloid-β (Aβ) and tau proteins accumulate within distinct neuronal systems in Alzheimer's
disease (AD). Although it is not clear why certain brain regions are more vulnerable to Aβ …

Omics approaches open new horizons in major depressive disorder: from biomarkers to precision medicine

F Stolfi, H Abreu, R Sinella, S Nembrini… - Frontiers in …, 2024 - frontiersin.org
Major depressive disorder (MDD) is a recurrent episodic mood disorder that represents the
third leading cause of disability worldwide. In MDD, several factors can simultaneously …

Longitudinal development of the human white matter structural connectome and its association with brain transcriptomic and cellular architecture

G Feng, R Chen, R Zhao, Y Li, L Ma, Y Wang… - Communications …, 2023 - nature.com
From childhood to adolescence, the spatiotemporal development pattern of the human brain
white matter connectome and its underlying transcriptomic and cellular mechanisms remain …

Mitochondrial function-associated genes underlie cortical atrophy in prodromal synucleinopathies

S Rahayel, C Tremblay, A Vo, B Misic, S Lehéricy… - Brain, 2023 - academic.oup.com
Isolated rapid eye movement sleep behaviour disorder (iRBD) is a sleep disorder
characterized by the loss of rapid eye movement sleep muscle atonia and the appearance of …

Exploring functional dysconnectivity in schizophrenia: alterations in eigenvector centrality mapping and insights into related genes from transcriptional profiles

Y Ji, M Cai, Y Zhou, J Ma, Y Zhang, Z Zhang, J Zhao… - Schizophrenia, 2024 - nature.com
Schizophrenia is a mental health disorder characterized by functional dysconnectivity.
Eigenvector centrality mapping (ECM) has been employed to investigate alterations in …

Fixel‐Based Analysis Reveals Whole‐Brain White Matter Abnormalities in Cervical Dystonia

GA Zito, C Tarrano, S Ouarab… - Movement …, 2023 - Wiley Online Library
Background Cervical dystonia (CD) is a form of isolated focal dystonia typically associated to
abnormal head, neck, and shoulder movements and postures. The complexity of the clinical …

Robust estimation of cortical similarity networks from brain MRI

I Sebenius, J Seidlitz, V Warrier, RAI Bethlehem… - Nature …, 2023 - nature.com
Structural similarity is a growing focus for magnetic resonance imaging (MRI) of
connectomes. Here we propose Morphometric INverse Divergence (MIND), a new method to …

Open datasets and code for multi-scale relations on structure, function and neuro-genetics in the human brain

A Jimenez-Marin, I Diez, A Erramuzpe, S Stramaglia… - Scientific Data, 2024 - nature.com
The human brain is an extremely complex network of structural and functional connections
that operate at multiple spatial and temporal scales. Investigating the relationship between …