Therapeutic approaches to mitigate the severe acute lung injury associated with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have rapidly entered …

Sepsis is a clinical syndrome characterized by a multisystem response to a pathogenic
assault due to underlying infection that involves a combination of interconnected …

This study aims to investigate the early changes in the immune systems of patients with
septic shock. A total of 243 patients with septic shock were included in this study. The …

Background Bacterial sepsis has been used as a prototype to understand the pathogenesis
of severe coronavirus disease 2019 (COVID-19). In addition, some management programs …

Opinion statement Cytokine storm syndromes require rapid diagnosis and treatment to limit
the morbidity and mortality caused by the hyperinflammatory state that characterizes these …

Summary Background Since December 2019, when coronavirus disease 2019 (COVID-19)
emerged in Wuhan and rapidly spread throughout the world, critically ill patients have a high …

Introduction Early sepsis is a life-threatening immune dysregulation believed to feature a
“cytokine storm” due to activation of pattern recognition receptors by pathogen and danger …

Rationale The immune profile of sepsis patients is incompletely understood and
hyperinflammation and hypoinflammation may occur concurrently or sequentially. Immune …

Sepsis is a life-threatening condition caused by the body's overwhelming response to an
infection, such as pneumonia or urinary tract infection. It occurs when the immune system …

Sepsis is characterized by a disproportionate host response to infection that often
culminates in multiple organ failure. Current concepts invoke a deregulated immune …