The integration of viral sequences into the host genome is an important driver of
tumorigenesis in many viral mediated cancers, notably cervical cancer and hepatocellular …

Background: Human papilloma virus (HPV) accounts for the most common cause of all virus-
associated human cancers. Here, we describe the first graphic user interface (GUI)-based …

Sporadic human breast cancer is the most common cancer to afflict women. Since the
discovery, decades ago, of the oncogenic mouse mammary tumour virus, there has been …

Other than an association with HPV infection, little is known about the genetic alterations
determining the development of penile cancer. Although penile cancer is rare in the …

Motivation Integration of viruses into infected host cell DNA can cause DNA damage and
disrupt genes. Recent cost reductions and growth of whole genome sequencing has …

Viral integration into the human genome upon infection is an important risk factor for various
human malignancies. We developed viral integration site detection tool called Virus-Clip …

Background Genetic recombination is a tremendous source of intrahost diversity in viruses
and is critical for their ability to rapidly adapt to new environments or fitness challenges …

Abstract Background Human papillomaviruses (HPVs) are a worldwide burden as they are a
widespread group of tumour viruses in humans. Having a tropism for mucosal tissues, high …

Hepatitis B virus (HBV) is still a worldwide health concern. While divergent factors are
involved in its pathogenesis, it is now clear that HBV RNAs, principally templates for viral …

Several pathogenic viruses such as hepatitis B and human immunodeficiency viruses may
integrate into the host genome. These virus/host integrations are detectable using paired …