Our lab has been intrigued by the fact that viral genomes often take on the role of mobile
elements to perpetuate their existence in a complex organism's genome. Multiple DNA …

Hepatocellular carcinoma (HCC) suffers from poor prognosis due to late detection and lack
of effective therapies. Chronic hepatitis B virus (HBV) infection is the major etiology of HCC …

Recent advances in sequencing technology, coupled with the relatively small genomes of
viruses, make routine sequencing of entire genomes in clinical and public health settings …

The occurrence of chimeric transcripts has been reported in many cancer cells and seen as
potential biomarkers and therapeutic targets. Modern high-throughput sequencing …

High-throughput cancer genomics and bioinformatics are revolutionizing our ability to profile
tumor samples. With next-generation sequencing (NGS) and high-performance computing …

Pathogens such as human papillomaviruses (HPVs) have co-evolved with their hosts and
form a molecular basis for common diseases. Persistent infection with the “high-risk” HPV …

Chronic virus infection is a state where the virus persists in the body after primary infection.
Primary infection can be asymptomatic and may remain unnoticed, but gradual replication of …

An estimated 17% of cancers worldwide are associated with infectious causes. The extent
and biological significance of viral presence/infection in actual tumor samples is generally …

Since the last decade, next generation sequencing (NGS) technologies have revolutionised
the field of genomics in biomedical research. Outcomes have been enhanced by the …

Around twenty percent of all cancer cases are contributed to infectious agents, mostly to
viruses. However, detection of viruses can be laborious, time-consuming, or require …