A comprehensive review on factors influences biogenesis, functions, therapeutic and clinical implications of exosomes

S Gurunathan, MH Kang, JH Kim - International journal of …, 2021 - Taylor & Francis
Exosomes are nanoscale-sized membrane vesicles secreted by almost all cell types into the
extracellular environment upon fusion of multivesicular bodies and plasma membrane …

A comprehensive insight into the role of exosomes in viral infection: dual faces bearing different functions

MH Saad, R Badierah, EM Redwan, EM El-Fakharany - Pharmaceutics, 2021 - mdpi.com
Extracellular vesicles (EVs) subtype, exosome is an extracellular nano-vesicle that sheds
from cells' surface and originates as intraluminal vesicles during endocytosis. Firstly, it was …

Extracellular vesicles and viruses: two intertwined entities

C Moulin, MJF Crupi, CS Ilkow, JC Bell… - International Journal of …, 2023 - mdpi.com
Viruses share many attributes in common with extracellular vesicles (EVs). The cellular
machinery that is used for EV production, packaging of substrates and secretion is also …

Extracellular vesicles in the pathogenesis of viral infections in humans

A Caobi, M Nair, AD Raymond - Viruses, 2020 - mdpi.com
Most cells can release extracellular vesicles (EVs), membrane vesicles containing various
proteins, nucleic acids, enzymes, and signaling molecules. The exchange of EVs between …

Multifunctional role of exosomes in viral diseases: From transmission to diagnosis and therapy

P Chaudhari, V Ghate, M Nampoothiri, S Lewis - Cellular signalling, 2022 - Elsevier
Efforts to discover antiviral drugs and diagnostic platforms have intensified to an
unprecedented level since the outbreak of COVID-19. Nano-sized endosomal vesicles …

HTLV-1 extracellular vesicles promote cell-to-cell contact

DO Pinto, C DeMarino, ML Pleet, M Cowen… - Frontiers in …, 2019 - frontiersin.org
Human T-cell leukemia virus-1 (HTLV-1) is a neglected and incurable retrovirus estimated to
infect 5 to 10 million worldwide. Specific indigenous Australian populations report infection …

Autophagy, EVs, and infections: a perfect question for a perfect time

ML Pleet, H Branscome, C DeMarino… - Frontiers in cellular …, 2018 - frontiersin.org
Autophagy, a highly conserved process, serves to maintain cellular homeostasis in
response to an extensive variety of internal and external stimuli. The classic, or canonical …

Navigating the complex landscape of ebola infection treatment: A review of emerging pharmacological approaches

F Almeida-Pinto, R Pinto, J Rocha - Infectious Diseases and Therapy, 2024 - Springer
In 1976 Ebola revealed itself to the world, marking the beginning of a series of localized
outbreaks. However, it was the Ebola outbreak that began in 2013 that incited fear and …

Intranasal Delivery of lincRNA-Cox2 siRNA Loaded Extracellular Vesicles Decreases Lipopolysaccharide-Induced Microglial Proliferation in Mice

K Liao, F Niu, RS Dagur, M He, C Tian, G Hu - Journal of Neuroimmune …, 2020 - Springer
Long non-coding RNAs (lncRNAs), including long intergenic non-coding RNAs (lincRNAs),
play an important regulatory role in controlling various biological processes. Both in vitro …

Dancing with Trojan horses: an interplay between the extracellular vesicles and viruses

RA Badierah, VN Uversky… - Journal of Biomolecular …, 2021 - Taylor & Francis
Extracellular vesicles (EVs) are membrane-encapsulated particles released by eukaryotic
and prokaryotic cells into the extracellular environment. Depending on their origin, size, and …