Oxidative stress is a component of many diseases, including atherosclerosis, chronic
obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small …

A biomarker describes a measurable indicator of a patient's clinical condition that can be
measured accurately and reproducibly. Biomarkers offer utility for diagnosis, prognosis …

Introduction: As the coronavirus disease 2019 (COVID-19) outbreak, identification of clinical
predictors of severe or fatal disease are necessary to enable risk stratification and optimize …

Introduction Cytokine adsorption using the CytoSorb® adsorber has been proposed in
various clinical settings including sepsis, ARDS, hyperinflammatory syndromes, cardiac …

In December 2019, a novel coronavirus, COVID-19, was discovered to be the causal agent
of a severe respiratory infection named SARS-CoV-2, and it has since been recognized …

Recent reports have showed that a proportion of patients with Coronavirus Disease 2019
(COVID-19) presented elevated leukocyte count. Clinical data about these patients is …

Backgroud The association between underlying comorbidities and cardiac injury and the
prognosis in coronavirus disease 2019 (COVID‐19) patients was assessed in this study …

Sepsis is a systemic inflammatory response syndrome with high mortality and morbidity
worldwide. In this study, we demonstrate that capsaicin not only suppresses inflammation in …

Notch signaling, a highly conserved pathway in mammals, is crucial for differentiation and
homeostasis of immune cells. Besides, this pathway is also directly involved in the …

Sepsis defined as a dysregulated immune response is a major cause of morbidity in
children. In sub-Saharan Africa, the clinical features of sepsis overlap with other frequent …