Genome-Wide Methylation Analysis Reveals a KCNK3-Prominent Causal Cascade on Hypertension
D Huang, W Shang, M Xu, Q Wan, J Zhang… - Circulation …, 2024 - Am Heart Assoc
BACKGROUND: Despite advances in understanding hypertension's genetic structure, how
noncoding genetic variants influence it remains unclear. Studying their interaction with DNA …
noncoding genetic variants influence it remains unclear. Studying their interaction with DNA …
Decreased Alu methylation in type 2 diabetes mellitus patients increases HbA1c levels
J Thongsroy, A Mutirangura - Journal of Clinical Laboratory …, 2023 - Wiley Online Library
Introduction Alu hypomethylation is a common epigenetic process that promotes genomic
instability with aging phenotypes, which leads to type 2 diabetes mellitus (type 2 DM) …
instability with aging phenotypes, which leads to type 2 diabetes mellitus (type 2 DM) …
Alu Methylation Patterns in Type 1 Diabetes: A Case-Control Study
A Katsanou, CA Kostoulas, E Liberopoulos… - Genes, 2023 - mdpi.com
Evidence suggests that genome-wide hypomethylation may promote genomic instability and
cellular senescence, leading to chronic complications in people with diabetes mellitus …
cellular senescence, leading to chronic complications in people with diabetes mellitus …
CpG methylation changes in Alu repetitive sequences in normal aging due to diastolic hypertension in human dermal fibroblasts from the facial area
S Jiraboonsri, P Hemvipat… - Biomedical …, 2024 - spandidos-publications.com
Aging fibroblasts, an important factor contributing to skin aging, are affected by numerous
mechanisms, including alterations in DNA methylation and age‑related diseases. The …
mechanisms, including alterations in DNA methylation and age‑related diseases. The …
Genome wide hypomethylation and youth-associated DNA gap reduction promoting DNA damage and senescence-associated pathogenesis
P Watcharanurak, A Mutirangura - Medical Research Archives, 2023 - esmed.org
Background: Age-associated epigenetic alteration is the underlying cause of DNA damage
in aging cells. Two types of youth-associated DNA-protection epigenetic marks, global …
in aging cells. Two types of youth-associated DNA-protection epigenetic marks, global …
[图书][B] The Role of B1 Methylation, Physiologic Replication Independent Endogenous DNA Double Strand Breaks (Phy-Rind-Edsb) and Laminin 511 E8 Proteins in …
J Meevassana - 2022 - search.proquest.com
Background: The rate of re-epithelialisation is a primary determinant of the morbidity and
mortality in patients with severe burn injuries. Alu elements are retrotransposons associated …
mortality in patients with severe burn injuries. Alu elements are retrotransposons associated …