Streptococcus pyogenes (ie, the group A Streptococcus) is a human-restricted and versatile bacterial pathogen that produces an impressive arsenal of both surface-expressed and …
M Saline, KEJ Rödström, G Fischer, VY Orekhov… - Nature …, 2010 - nature.com
Superantigens (SAgs) are bacterial toxins that interact with immunoreceptors, T cell receptor (TCR) and major histocompatibility complex (MHC) class II, conventionally through the …
Superantigens are bacterial proteins that generate a powerful immune response by binding to Major Histocompatibility Complex class II molecules on antigen-presenting cells and T …
SA Richman, DM Kranz - Biomolecular engineering, 2007 - Elsevier
The use of T cell receptors (TCRs) as potential therapeutic agents provides an opportunity to target a greatly expanded array of antigens, compared to those now targeted with …
G Marone, FW Rossi, A Pecoraro, V Pucino… - Vaccines, 2020 - mdpi.com
Human lung mast cells (HLMCs) express the high-affinity receptor FcεRI for IgE and are involved in chronic pulmonary diseases occurring at high frequency among HIV-infected …
R Chen, W Tong, J Mintseris, L Li… - … : Structure, Function, and …, 2003 - Wiley Online Library
The CAPRI Challenge is a blind test of protein–protein‐docking algorithms that predict the complex structure from the crystal structures of the interacting proteins. We participated in …
K Petersson, H Pettersson, NJ Skartved… - The Journal of …, 2003 - journals.aai.org
Staphylococcal enterotoxin H (SEH) is a bacterial superantigen secreted by Staphylococcus aureus. Superantigens are presented on the MHC class II and activate large amounts of T …
K Petersson, G Forsberg… - Scandinavian journal of …, 2004 - Wiley Online Library
Superantigens (SAGs) cause a massive T‐cell proliferation by simultaneously binding to major histocompatibility complex (MHC) class II on antigen‐presenting cells and T‐cell …
JL Hayworth, DM Mazzuca, SM Vareki… - Immunology and cell …, 2012 - Wiley Online Library
Invariant NKT (iNKT) cells are infrequent but important immunomodulatory lymphocytes that exhibit CD1d‐restricted reactivity with glycolipid Ags. iNKT cells express a unique T‐cell …