Background Immunotherapy has been used to improve patient immune function, inhibit
tumor growth and has become a highly promising method of cancer treatment. Highly …

Bacterial superantigens are protein toxins with an ability to cause serious diseases in
humans by activating a large number of T cells. Streptococcus dysgalactiae-derived mitogen …

The macromolecular docking problem that must be solved for experimental biologists is
prediction of the structures of complexes for which the components are known or reliably …

Protein engineering is becoming increasingly important for pharmaceutical applications
where controlling the specificity and affinity of engineered proteins is required to create …

Im ersten Teil dieses Kapitels befassen wir uns mit den zellulären Reaktionswegen, die von
den verschiedenen Zelltypen genutzt werden, um Peptid: MHC-Komplexe zu erzeugen, die …

Abstract Background The glycoprotein D (gD) is essential for Herpes B virus (BV) entry into
mammalian cells. Nectin-1, an HSV-1 gD receptor, is found to be the receptor which …

Abstract<? Pub Inc> Superantigens (SAgs) are implicated in the initiation of many diseases,
including Kawasaki disease (KD), a multi-system vasculitis that leads to persistent …

Abstract Analysis of T cell receptor β variable region (TCRBV) gene rearrangement is useful
for clonal assessment of abnormal T cell proliferations in various diseases. However, most …

Streptococcus pyogenes is adapted for persistence in humans. It typically colonizes the
tonsils and skin, and humans are the only known reservoir. S. pyogenes can cause a wide …

Staphylococcus aureus produces a family of at least 21 distinct superantigens (SAgs) which
include staphylococcal enterotoxins (SEs), staphylococcal enterotoxin-like toxins (SEls), and …