Cytokine storm in COVID-19: the current evidence and treatment strategies

Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is the pathogen that causes
coronavirus disease 2019 (COVID-19). As of 25 May 2020, the outbreak of COVID-19 has …

Organ-specific manifestations of COVID-19 infection

M Gavriatopoulou, E Korompoki, D Fotiou… - Clinical and …, 2020 - Springer
Although COVID-19 presents primarily as a lower respiratory tract infection transmitted via
air droplets, increasing data suggest multiorgan involvement in patients that are infected …

Demographic risk factors for COVID-19 infection, severity, ICU admission and death: a meta-analysis of 59 studies

BG Pijls, S Jolani, A Atherley, RT Derckx, JIR Dijkstra… - BMJ open, 2021 - bmjopen.bmj.com
Objective We aimed to describe the associations of age and sex with the risk of COVID-19 in
different severity stages ranging from infection to death. Design Systematic review and meta …

Biomarkers associated with COVID-19 disease progression

G Ponti, M Maccaferri, C Ruini, A Tomasi… - Critical reviews in …, 2020 - Taylor & Francis
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a scientific, medical, and
social challenge. The complexity of the severe acute respiratory syndrome coronavirus 2 …

Severity and mortality of COVID 19 in patients with diabetes, hypertension and cardiovascular disease: a meta-analysis

B de Almeida-Pititto, PM Dualib, L Zajdenverg… - Diabetology & metabolic …, 2020 - Springer
Background The aim of this study is to evaluate the impact of diabetes, hypertension,
cardiovascular disease and the use of angiotensin converting enzyme inhibitors/angiotensin …

Acute SARS-CoV-2 infection impairs dendritic cell and T cell responses

R Zhou, KKW To, YC Wong, L Liu, B Zhou, X Li… - Immunity, 2020 - cell.com
The SARS-CoV-2 pandemic has resulted in millions of infections, yet the role of host
immune responses in early COVID-19 pathogenesis remains unclear. By investigating 17 …

Predictors of in-hospital COVID-19 mortality: A comprehensive systematic review and meta-analysis exploring differences by age, sex and health conditions

AE Mesas, I Cavero-Redondo, C Álvarez-Bueno… - PloS one, 2020 - journals.plos.org
Objective Risk factors for in-hospital mortality in confirmed COVID-19 patients have been
summarized in numerous meta-analyses, but it is still unclear whether they vary according to …

Deciphering the COVID‐19 cytokine storm: systematic review and meta‐analysis

R Mulchandani, T Lyngdoh… - European journal of …, 2021 - Wiley Online Library
Introduction The coronavirus pandemic has affected more than 20 million people so far.
Elevated cytokines and suppressed immune responses have been hypothesized to set off a …

Lymphocyte subset counts in COVID‐19 patients: a meta‐analysis

W Huang, J Berube, M McNamara, S Saksena… - Cytometry part …, 2020 - Wiley Online Library
A reduced peripheral blood absolute lymphocyte count with an elevated neutrophil count
has been a consistent observation in hospitalized coronavirus disease 2019 (COVID‐19) …

Varicella zoster virus reactivation following COVID-19 vaccination: a systematic review of case reports

K Katsikas Triantafyllidis, P Giannos, IT Mian… - Vaccines, 2021 - mdpi.com
The newly developed COVID-19 vaccines have established a safe profile, yet some
individuals experience a wide range of adverse events. Recently, reactivation of varicella …