Competition between enzymatic and non-enzymatic electrochemical determination of cholesterol

MA Hefnawy, SA Fadlallah, RM El-Sherif… - Journal of …, 2023 - Elsevier
Cholesterol is considered an essential component in animal bodies that plays a vital role in
hormone production and creating vitamin D. The elevated blood cholesterol level increases …

CRISPR-based biosensors for pathogenic biosafety

H Yang, R Ledesma-Amaro, H Gao, Y Ren… - Biosensors and …, 2023 - Elsevier
Pathogenic biosafety is a worldwide concern. Tools for analyzing pathogenic biosafety, that
are precise, rapid and field-deployable, are highly demanded. Recently developed …

[HTML][HTML] CASCADE: Naked eye-detection of SARS-CoV-2 using Cas13a and gold nanoparticles

M López-Valls, C Escalona-Noguero… - Analytica chimica …, 2022 - Elsevier
The COVID-19 pandemic has brought to light the need for fast and sensitive detection
methods to prevent the spread of pathogens. The scientific community is making a great …

Architecting of an aptasensor for the staphylococcus aureus analysis by modification of the screen-printed carbon electrode with aptamer/Ag–Cs-Gr QDs/NTiO2

M Ghalkhani, E Sohouli, SS Khaloo, MH Vaziri - Chemosphere, 2022 - Elsevier
Given the many issues bacterial infections cause to humans and the necessity for their
detection, in this work we developed a robust aptasensor for prompt, ultrasensitive, and …

Electrochemical biosensor for detecting pathogenic bacteria based on a hybridization chain reaction and CRISPR-Cas12a

X Liu, S Bu, J Feng, H Wei, Z Wang, X Li… - Analytical and …, 2022 - Springer
Abstract In this study, Lba Cas12a (Cpf1) as one of the CRISPR systems from
Lachnospiraceae bacterium was coupled with a hybridization chain reaction (HCR) to …

Argonaute-DNAzyme tandem biosensing for highly sensitive and simultaneous dual-gene detection of methicillin-resistant Staphylococcus aureus

Y Li, X Tang, N Wang, Z Zhao, S Man, L Zhu… - Biosensors and …, 2024 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA), a common zoonotic multidrug-resistant
bacterium, puts a great threat to public health and food safety. Rapid and reliable detection …

Next-generation CRISPR-based diagnostic tools for human diseases

T Wang, Z Wang, L Bai, X Zhang, H Zhang… - TrAC Trends in …, 2023 - Elsevier
Accurate diagnosis of human diseases is crucial for effective prevention, clinical treatment,
and prognosis. The World Health Organization (WHO) has provided guidelines for molecular …

CRISPR/Cas-powered amplification-free detection of nucleic acids: current state of the art, challenges, and futuristic perspectives

Y Li, Y Liu, X Tang, J Qiao, J Kou, S Man, L Zhu… - ACS …, 2023 - ACS Publications
CRISPR/Cas system is becoming an increasingly influential technology that has been
repositioned in nucleic acid detection. A preamplification step is usually required to improve …

A CRISPR/dCas9‐enabled, on‐site, visual, and bimodal biosensing strategy for ultrasensitive and self‐validating detection of foodborne pathogenic bacteria

Y Li, J Qiao, Z Zhao, Q Zhang, W Zhang, S Man… - Food …, 2023 - Wiley Online Library
It is imperative to develop practicable pathogenic bacteria detection methods. We devised a
biosensor for the ultrasensitive detection of Salmonella typhimurium (S. typhi), termed as …

“Three-in-one” Zr-MOF multifunctional carrier-mediated fluorescent and colorimetric dual-signal readout biosensing platform to enhance analytical performance

L Ren, F Hong, L Zeng, Y Chen - ACS Applied Materials & …, 2022 - ACS Publications
To address the urgent demand for sensitive and stable detection applications, significant
efforts have been made in the development of dual-signal readout assays for precise target …