Mitochondrial dysfunctions, oxidative stress and neuroinflammation as therapeutic targets for neurodegenerative diseases: an update on current advances and …

MU Rehman, N Sehar, NJ Dar, A Khan, A Arafah… - Neuroscience & …, 2023 - Elsevier
Neurodegenerative diseases (NDs) such as Alzheimer disease (AD), Parkinson disease
(PD), and Huntington disease (HD) represent a major socio-economic challenge in view of …

Tear biomarkers in Alzheimer's and Parkinson's diseases, and multiple sclerosis: implications for diagnosis (systematic review)

A Król-Grzymała, E Sienkiewicz-Szłapka… - International Journal of …, 2022 - mdpi.com
Biological material is one of the most important aspects that allow for the correct diagnosis of
the disease, and tears are an interesting subject of research because of the simplicity of …

Role of the gut–brain axis, gut microbial composition, diet, and probiotic intervention in Parkinson's disease

S Thangaleela, BS Sivamaruthi, P Kesika, M Bharathi… - Microorganisms, 2022 - mdpi.com
Parkinson's disease (PD) is the second-most prevalent neurodegenerative or
neuropsychiatric disease, affecting 1% of seniors worldwide. The gut microbiota (GM) is one …

Intranasal insulin improves mitochondrial function and attenuates motor deficits in a rat 6‐OHDA model of Parkinson's disease

F Iravanpour, L Dargahi, M Rezaei… - CNS Neuroscience …, 2021 - Wiley Online Library
Aims Experimental and clinical evidences demonstrate that common dysregulated pathways
are involved in Parkinson's disease (PD) and type 2 diabetes. Recently, insulin treatment …

Detection and classification of early stages of Parkinson's disease through wearable sensors and machine learning

A Shcherbak, E Kovalenko… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Parkinson's disease (PD) is a neurodegenerative disease which is among the most spread
and growing common neurodegenerative disorders. It significantly limits the physical and …

Searching for biomarkers in the blood of patients at risk of developing Parkinson's disease at the Prodromal Stage

EA Katunina, V Blokhin, MR Nodel, EN Pavlova… - International Journal of …, 2023 - mdpi.com
Parkinson's disease (PD) is diagnosed many years after its onset, under a significant
degradation of the nigrostriatal dopaminergic system, responsible for the regulation of motor …

Correlation of glymphatic system abnormalities with Parkinson's disease progression: a clinical study based on non-invasive fMRI

JC Meng, MQ Shen, YL Lu, HX Feng, XY Chen… - Journal of …, 2024 - Springer
Background The glymphatic system is reportedly involved in Parkinson's disease (PD).
Based on previous studies, we aimed to confirm the correlation between the glymphatic …

Engineering nanoprobes for magnetic resonance imaging of brain diseases

J Zhang, L Yu, M Yu, D Yu, Y Chen, J Zhang - Chemical Engineering …, 2023 - Elsevier
Increasing brain disease incidence has become a common cause of disability and death
worldwide. Early diagnosis of brain diseases is crucial to improve the prognosis of patients …

Parkinson's disease detection and classification using EEG based on deep CNN-LSTM model

K Li, B Ao, X Wu, Q Wen, E Ul Haq… - … and Genetic Engineering …, 2023 - Taylor & Francis
The progressive loss of motor function in the brain is a hallmark of Parkinson's disease (PD).
Electroencephalogram (EEG) signals are commonly used for early diagnosis since they are …

Parkinson's disease detection based on multi-pattern analysis and multi-scale convolutional neural networks

L Qiu, J Li, J Pan - Frontiers in Neuroscience, 2022 - frontiersin.org
Parkinson's disease (PD) is a complex neurodegenerative disease. At present, the early
diagnosis of PD is still extremely challenging, and there is still a lack of consensus on the …