Metabolic syndrome (MS) is a chronic non‐infective syndrome characterised clinically by a set of vascular risk factors that include insulin resistance, hypertension, abdominal obesity …
Adipocytes undergo intense energetic stress in obesity resulting in loss of mitochondrial mass and function. We have found that adipocytes respond to mitochondrial stress by …
DE Handy, J Loscalzo - Free Radical Biology and Medicine, 2022 - Elsevier
Abstract Glutathione peroxidase 1 (GPx1) is an important cellular antioxidant enzyme that is found in the cytoplasm and mitochondria of mammalian cells. Like most selenoenzymes, it …
E Dubois-Deruy, V Peugnet, A Turkieh, F Pinet - Antioxidants, 2020 - mdpi.com
Reactive oxygen species (ROS) are subcellular messengers in signal transductions pathways with both beneficial and deleterious roles. ROS are generated as a by-product of …
D Rotariu, EE Babes, DM Tit, M Moisi, C Bustea… - Biomedicine & …, 2022 - Elsevier
Oxidative stress is a complex biological process characterized by the excessive production of reactive oxygen species (ROS) that act as destroyers of the REDOX balance in the body …
T Zhao, W Wu, L Sui, Q Huang, Y Nan, J Liu, K Ai - Bioactive Materials, 2022 - Elsevier
Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial infarction, but morbidity and mortality of acute myocardial infarction are still high …
A Shaito, K Aramouni, R Assaf, A Parenti, A Orekhov… - 2022 - qspace.qu.edu.qa
Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better understanding of the mechanisms underlying CVD is key for better management or …
Cardiovascular diseases (CVDs) are the leading cause of human mortality worldwide. Oxidative stress and inflammation are pathophysiological processes involved in the …
CE Kosmas, MD Bousvarou… - Journal of …, 2023 - journals.sagepub.com
Insulin resistance (IR) and cardiovascular disease (CVD) represent two universal public health hazards, especially in today's Western societies. A causal-effect relationship has …