Abstract Type 2 diabetes (T2D) is a critical risk factor for peripheral artery disease (PAD).
However, the sex differences in genetic basis, causality, and underlying mechanisms of the …

It remains unclear whether human species exhibits sexual dimorphism in brain activities,
and how the dimorphisms associated with sex-characterized behaviors. Here, in a large …

The evolving view of gut microbiota has shifted toward describing the colonic flora as a
dynamic organ in continuous interaction with systemic physiologic processes. Alterations of …

Inspired by the mechanistic correlations between superoxide dismutase 1 (SOD1) and lipid
metabolism, the associations of SOD1 single nucleotide polymorphisms (SNPs) with …

Sex is arguably the most important differentiating characteristic in most mammalian species,
separating populations into different groups, with varying behaviors, morphologies, and …

Science has come a long way with regard to the consideration of sex differences in clinical
and preclinical research, but one field remains behind the curve: human statistical genetics …

Background Alcohol consumption behaviors and alcohol use disorder risk and presentation
differ by sex, and these complex traits are associated with blood concentrations of the …

Cancer is one of the complex disorders that show sexual dimorphism in its susceptibility,
clinical course, response to treatment, and prognosis. Most cancers show a disadvantage for …

In this chapter, the author briefly covers the basic features of the HumanMethylation
BeadChip array platform, such as its method of measuring DNA methylation, manufacturing …

Purpose: To investigate for the first time the association of collagen COL4A3 (rs55703767),
COL5A1 (rs7044529), and COL4A4 (rs2229813) variants with response to corneal collagen …