Zinc is one of the most abundant metal ions in the central nervous system (CNS), where it
plays a crucial role in both physiological and pathological brain functions. Zinc promotes …

Major depressive disorder (MDD) is a heterogeneous disease affecting one out of five
individuals and is the leading cause of disability worldwide. Presently, MDD is considered a …

Anhedonia is one of the core symptoms of major depressive disorder (MDD), which is often
inadequately treated by traditional antidepressants. The modern framework of anhedonia …

Positive, prosocial interactions are essential for survival, development, and well-being.
These intricate and complex behaviors are mediated by an amalgamation of neural circuit …

Background Emerging evidence points to a central role of mitochondria in psychiatric
disorders. However, little is known about the molecular players that regulate mitochondria in …

The cerebellum is involved in many motor, autonomic and cognitive functions, and new
tasks that have a cerebellar contribution are discovered on a regular basis. Simultaneously …

Exposure to prolonged stress in critical developmental periods induces heightened
vulnerability to psychiatric disorders, which may have sex-specific consequences. Here we …

Background Verbascoside is a natural and water-soluble phenylethanoid glycoside found in
several medicinal plants. It has extensive pharmacological effects, including antioxidative …

Although cerebellar alterations have been implicated in stress symptoms, the exact
contribution of the cerebellum to stress symptoms remains to be elucidated. Here, we …

Major depressive disorder (MDD) is one of the most common and disabling mental
disorders, and current strategies remain inadequate. Although mesenchymal stromal cells …