Introduction Indolizines are structural isomers with indoles. Although several indole-based
commercial drugs are available in the market, none of the indolizine-based drugs are …

Thiazolidinedione (TZD) containing derivatives have been proved to be promising
anticancer agents in preclinical and clinical evaluation phases. Hybrid molecules not just …

Here we report the surprising discovery that high-energy vinyl carbocations can be
generated under strongly basic conditions, and that they engage in intramolecular sp3 C–H …

Herein, molecular hybridization strategy was utilized in the design of new benzosuberone-
thiazole derivatives. The structures of the synthesized hybrids were determined on the basis …

Heterocyclic derivatives serve as the fundamental components of both natural and synthetic
drugs. Enaminones play a crucial role as foundational units in the synthesis of numerous …

Visible light-mediated selective and efficient oxidation of various primary/secondary benzyl
alcohols to aldehydes/ketones and oxidative dehydrogenation (ODH) of partially saturated …

Introduction Bipyrazole is constituted from two pyrazole units either in their fully aromatic or
partially hydrogenated forms. Pyrazoles are widely available in pharmaceutical and …

Abstract Head and neck Squamous Cell Carcinoma (HNSCC) is a growing concern
worldwide and MAPKAPK2/MK2 (Mitogen-Activated Protein Kinase Activated Protein Kinase …

Hydrazonoyl halides have been known for their ability to react with different reagents to
afford wide range of bioactive heterocyclic systems as thiazoles and imidazopyrazoles. This …

A novel, expedient and effective methodology for the synthesis of distinctly substituted 6, 7-
dihydro-5 H-benzo [6, 7] cyclohepta [1, 2-b] pyridine and 5, 6-dihydrobenzo [h] quinoline …