Targeting the RdRp of emerging RNA viruses: the structure-based drug design challenge

F Picarazzi, I Vicenti, F Saladini, M Zazzi, M Mori - Molecules, 2020 - mdpi.com
The RNA-dependent RNA polymerase (RdRp) is an essential enzyme for the viral
replication process, catalyzing the viral RNA synthesis using a metal ion-dependent …

High-throughput sequencing in plant disease management: a comprehensive review of benefits, challenges, and future perspectives

MM Nizamani, Q Zhang, G Muhae-Ud-Din… - Phytopathology …, 2023 - Springer
High-throughput sequencing (HTS) has instigated a paradigm shift in plant pathology,
showcasing its transformative role in the management of plant diseases. As a powerful tool …

A novel tiled amplicon sequencing assay targeting the tomato brown rugose fruit virus (ToBRFV) genome reveals widespread distribution in municipal wastewater …

D Nash, I Ellmen, JJ Knapp, R Menon, AK Overton… - Viruses, 2024 - mdpi.com
Tomato Brown Rugose Fruit Virus (ToBRFV) is a plant pathogen that infects important
Solanaceae crop species and can dramatically reduce tomato crop yields. The ToBRFV has …

Bacteriophages in biological wastewater treatment systems: occurrence, characterization, and function

V Runa, J Wenk, S Bengtsson, BV Jones… - Frontiers in …, 2021 - frontiersin.org
Phage bacteria interactions can affect structure, dynamics, and function of microbial
communities. In the context of biological wastewater treatment (BWT), the presence of …

[HTML][HTML] The role of mobile genetic elements in organic micropollutant degradation during biological wastewater treatment

ABR Miguel, MSM Jetten, CU Welte - Water Research X, 2020 - Elsevier
Wastewater treatment plants (WWTPs) are crucial for producing clean effluents from
polluting sources such as hospitals, industries, and municipalities. In recent decades, many …

Evaluation of haplotype callers for next-generation sequencing of viruses

A Eliseev, KM Gibson, P Avdeyev, D Novik… - Infection, Genetics and …, 2020 - Elsevier
Currently, the standard practice for assembling next-generation sequencing (NGS) reads of
viral genomes is to summarize thousands of individual short reads into a single consensus …

Next Generation Sequencing Approaches to Characterize the Respiratory Tract Virome

N Sandybayev, V Beloussov, V Strochkov… - Microorganisms, 2022 - mdpi.com
The COVID-19 pandemic and heightened perception of the risk of emerging viral infections
have boosted the efforts to better understand the virome or complete repertoire of viruses in …

Helicobacter bilis Contributes to the Occurrence of Inflammatory Bowel Disease by Inducing Host Immune Disorders

W Peng, X Zhao, X Li - BioMed Research International, 2022 - Wiley Online Library
Gut microbiota coevolve with humans to achieve a symbiotic relationship, which ultimately
leads to physiological homeostasis. A variety of diseases can occur once this balance is …

Whole genome strategies and bioremediation insight into dehalogenase-producing bacteria

HA Oyewusi, RA Wahab, F Huyop - Molecular biology reports, 2021 - Springer
An integral approach to decoding both culturable and uncultured microorganisms' metabolic
activity involves the whole genome sequencing (WGS) of individual/complex microbial …

[PDF][PDF] 进化树在细菌亲缘关系分析中的应用研究

迟文静, 刘宜昕, 王粟, 刘涛, 赵虎, 张艳梅 - 检验医学, 2020 - caivd-org.cn
随着生物技术的发展与应用, 许多未知的细菌陆续被发现. 同时, 随着环境的变化,
一些已知的细菌不断产生新的致病或耐药表型. 面对细菌日益复杂的威胁, 开展细菌进化及其与 …