[HTML][HTML] The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
MF Osuchowski, MS Winkler, T Skirecki… - The Lancet …, 2021 - thelancet.com
The zoonotic SARS-CoV-2 virus that causes COVID-19 continues to spread worldwide, with
devastating consequences. While the medical community has gained insight into the …
devastating consequences. While the medical community has gained insight into the …
T‐cell responses and therapies against SARS‐CoV‐2 infection
Abstract Coronavirus disease 2019 (COVID‐19) is caused by SARS‐CoV‐2, a novel
coronavirus strain. Some studies suggest that COVID‐19 could be an immune‐related …
coronavirus strain. Some studies suggest that COVID‐19 could be an immune‐related …
Cytokine profile and disease severity in patients with COVID-19
Cytokine dysregulation is the proposed mechanism for Coronavirus disease 2019 (COVID-
19). The aim of this study was to evaluate the serum levels of interferon (IFN)-γ, interleukin …
19). The aim of this study was to evaluate the serum levels of interferon (IFN)-γ, interleukin …
[HTML][HTML] Circulating exosomes are strongly involved in SARS-CoV-2 infection
Knowledge of the host response to the novel coronavirus SARS-CoV-2 remains limited,
hindering the understanding of COVID-19 pathogenesis and the development of therapeutic …
hindering the understanding of COVID-19 pathogenesis and the development of therapeutic …
[HTML][HTML] Different innate and adaptive immune responses to SARS-CoV-2 infection of asymptomatic, mild, and severe cases
R Carsetti, S Zaffina, E Piano Mortari, S Terreri… - Frontiers in …, 2020 - frontiersin.org
SARS-CoV-2 is a novel coronavirus, not encountered before by humans. The wide spectrum
of clinical expression of SARS-CoV-2 illness suggests that individual immune responses to …
of clinical expression of SARS-CoV-2 illness suggests that individual immune responses to …
[HTML][HTML] An aberrant STAT pathway is central to COVID-19
T Matsuyama, SP Kubli, SK Yoshinaga… - Cell Death & …, 2020 - nature.com
COVID-19 is caused by SARS-CoV-2 infection and characterized by diverse clinical
symptoms. Type I interferon (IFN-I) production is impaired and severe cases lead to ARDS …
symptoms. Type I interferon (IFN-I) production is impaired and severe cases lead to ARDS …
[HTML][HTML] COVID-19 and the role of cytokines in this disease
A Hasanvand - Inflammopharmacology, 2022 - Springer
Studies have shown that SARS-CoV-2 has the ability to activate and mature proinflammatory
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …
Camostat mesylate against SARS‐CoV‐2 and COVID‐19—Rationale, dosing and safety
P Breining, AL Frølund, JF Højen… - Basic & clinical …, 2021 - Wiley Online Library
The coronavirus responsible for COVID‐19, SARS‐CoV‐2, utilizes a viral membrane spike
protein for host cell entry. For the virus to engage in host membrane fusion, SARS‐CoV‐2 …
protein for host cell entry. For the virus to engage in host membrane fusion, SARS‐CoV‐2 …
[HTML][HTML] SARS-CoV-2 mediated endothelial dysfunction: the potential role of chronic oxidative stress
Endothelial cells have emerged as key players in SARS-CoV-2 infection and COVID-19
inflammatory pathologies. Dysfunctional endothelial cells can promote chronic inflammation …
inflammatory pathologies. Dysfunctional endothelial cells can promote chronic inflammation …
[HTML][HTML] COVID-19-associated acute respiratory distress syndrome (CARDS): Current knowledge on pathophysiology and ICU treatment–A narrative review
CA Pfortmueller, T Spinetti, RD Urman… - Best Practice & …, 2021 - Elsevier
Abstract (163 words) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
induces coronavirus-19 disease (COVID-19) and is a major health concern. Following two …
induces coronavirus-19 disease (COVID-19) and is a major health concern. Following two …