Gastric cancer (GC) is one of the most common malignancies worldwide. Most patients are
diagnosed at advanced stages due to the subtle symptoms of earlier disease and the low …

The tumor microenvironment is proposed to contribute substantially to the progression of
cancers, including breast cancer. Cancer‐associated fibroblasts (CAFs) are the most …

Importance Cancers are a leading cause of mortality, accounting for nearly 10 million annual
deaths worldwide, or 1 in 6 deaths. Cancers also negatively affect countries' economic …

Platinum-based chemotherapy is the standard first-line treatment for advanced esophageal
squamous cell carcinoma (ESCC). In this phase 3 study (ClinicalTrial. gov: NCT03829969) …

Background Cancer has been the leading cause of death since 2010 in China, with
increasing incidence, mortality, and burden. We aimed to assess national and subnational …

Background Resistance to ferroptosis, a regulated cell death caused by iron‐dependent
excessive accumulation of lipid peroxides, has recently been linked to lung adenocarcinoma …

Background Cancer cells selectively promote the translation of oncogenic transcripts to
stimulate cancer progression. Although growing evidence has revealed that tRNA …

Abstract Background N‐acetyltransferase 10 (NAT10) is the only enzyme known to mediate
the N4‐acetylcytidine (ac4C) modification of mRNA and is crucial for mRNA stability and …

PURPOSE The CHOICE-01 study investigated the efficacy and safety of toripalimab in
combination with chemotherapy as a first-line treatment for advanced non–small-cell lung …

Abstract Background Neutrophil extracellular traps (NETs) are considered significant
contributors to cancer progression, especially metastasis. However, it is still unclear whether …