The unique morphological and excitable properties of nerve cells endow them with
specialized properties that permit the reception, transmission, and storage of information. It …

This article reviews findings up to the end of 1997 about the inducible transcription factors
(ITFs) c-Jun, JunB, JunD, c-Fos, FosB, Fra-1, Fra-2, Krox-20 (Egr-2) and Krox-24 (NGFI-A …

An unusual pattern in a nucleic acid or protein sequence or a region of strong similarity
shared by two or more sequences may have biological significance. It is therefore desirable …

Binding of the human transcription factor Jun/AP-1 to a conserved 8 bp nucleotide sequence
(TRE) is responsible for increased transcription of different cellular genes in response to …

The mechanism by which the calcium influx signal, triggered by membrane depolarization, is
transduced to the nucleus to activate c-fos proto-oncogene transcription has been …

RECENT studies in invertebrates indicate that a rapid genomic response to neuronal
stimulation has a critical role in long-term changes in synaptic efficacy1. Because several of …

Cell lines stably transfected with metal inducible, MT-fos chimeric genes were used to study
the ability of the c-fos gene product, Fos, to act as a transcriptional trans-activator. In …

The c-jun and c-fos proto-oncogenes encode proteins that form a complex which regulates
transcription from promoters containing AP-1 activation elements. c&n has specific DNA …

Excitation of neurons results in a series of finely orchestrated responses that occur over a
time frame ranging from fractions of a second to hours or days. In the short term, stimulation …

Mutations at the mouse tottering (tg) locus cause a delayed-onset, recessive neurological
disorder resulting in ataxia, motor seizures, and behavioral absence seizures resembling …