Engineering Cell Membrane‐Cloaked Catalysts as Multifaceted Artificial Peroxisomes for Biomedical Applications

D Yang, Y Tang, B Zhu, H Pang, X Rong… - Advanced …, 2023 - Wiley Online Library
Artificial peroxisomes (APEXs) or peroxisome mimics have caught a lot of attention in
nanomedicine and biomaterial science in the last decade, which have great potential in …

Site-specific inhibition of neutrophilic inflammation by low-dose nanotherapy for immunoregulatory treatment of asthma

L Li, Y Ma, Y Hu, P Wang, S Han, X Zhang, J Zhang - Nano Today, 2023 - Elsevier
Asthma, one of the most common lung diseases, remains a serious global health problem.
Currently there is still an urgent need for effective and safe therapies against severe asthma …

Cargo-free particles divert neutrophil-platelet aggregates to reduce thromboinflammation

AL Banka, MV Guevara, ER Brannon… - Nature …, 2023 - nature.com
The combination of inflammation and thrombosis is a hallmark of many cardiovascular
diseases. Under such conditions, platelets are recruited to an area of inflammation by …

Tetrahedral framework nucleic acid nanomaterials reduce the inflammatory damage in sepsis by inhibiting pyroptosis

X Chen, J He, Y Xie, T Zhang, S Li, Y Zhao… - Cell …, 2023 - Wiley Online Library
Sepsis is a highly lethal condition and is caused by the dysregulation of the body's immune
response to infection. Indeed, sepsis remains the leading cause of death in severely ill …

Arthritic Microenvironment‐Dictated Fate Decisions for Stem Cells in Cartilage Repair

S He, H Deng, P Li, J Hu, Y Yang, Z Xu, S Liu… - Advanced …, 2023 - Wiley Online Library
The microenvironment and stem cell fate guidance of post‐traumatic articular cartilage
regeneration is primarily the focus of cartilage tissue engineering. In articular cartilage, stem …

The therapeutic potential of immunoengineering for systemic autoimmunity

DA McBride, RM Jones, N Bottini… - Nature Reviews …, 2024 - nature.com
Disease-modifying drugs have transformed the treatment options for many systemic
autoimmune diseases. However, an evolving understanding of disease mechanisms, which …

Emerging strategies for nanomedicine in autoimmunity

AS Thatte, MM Billingsley, D Weissman… - Advanced Drug Delivery …, 2024 - Elsevier
Autoimmune disorders have risen to be among the most prevalent chronic diseases across
the globe, affecting approximately 5–7% of the population. As autoimmune diseases steadily …

Nanomaterials for Periodontal Tissue Regeneration: Progress, Challenges and Future Perspectives

C Zong, A Bronckaers, G Willems, H He… - Journal of Functional …, 2023 - mdpi.com
Bioactive nanomaterials are increasingly being applied in oral health research. Specifically,
they have shown great potential for periodontal tissue regeneration and have substantially …

Development of protein–polymer conjugate nanoparticles for modulation of dendritic cell phenotype and Antigen-Specific CD4 T cell responses

BL Scotland, AL Cottingham, JJM Lasola… - ACS Applied Polymer …, 2023 - ACS Publications
Polymeric nanoparticles (NPs) composed of poly (lactic-co-glycolic acid)(PLGA) have found
success in modulating antigen (Ag)-specific T cell responses for the treatment multiple …

Harnessing Immunomodulatory Polymers for Treatment of Autoimmunity, Allergy, and Transplant Rejection

AB Tu, G Krishna, KR Smith… - Annual Review of …, 2024 - annualreviews.org
Autoimmunity, allergy, and transplant rejection are a collection of chronic diseases that are
currently incurable, drastically decrease patient quality of life, and consume considerable …