Women's health concerns are generally underrepresented in basic and translational
research, but reproductive health in particular has been hampered by a lack of …

Fibrosis is an intrinsic response to chronic injury, maintaining organ integrity when extensive
necrosis or apoptosis occurs. With protracted damage, fibrosis can progress toward …

Mesenchymal stem cells (MSCs) can be cultured relatively easily and can be obtained not
only from the bone marrow, but also from medical waste such as adipose tissue and …

We describe a novel therapeutic approach for cirrhosis using mesenchymal stem cells
(MSCs) and colony-stimulating factor-1-induced bone marrow-derived macrophages (id …

Abstract Glycogen Storage Disease 1a (GSD1a) is a rare, inherited metabolic disorder
caused by deficiency of glucose 6-phosphatase (G6Pase-α). G6Pase-α is critical for …

The emerging field of regenerative medicine offers innovative methods of cell therapy and
tissue/organ engineering as a novel approach to liver disease treatment. The ultimate …

With evidence from a large number of animal models and clinical trials, it is now beyond
debate that liver fibrosis and even cirrhosis are potentially reversible if the underlying cause …

Various factors, including viral and bacterial infections, autoimmune responses, diabetes,
drugs, alcohol abuse, and fat deposition, can damage liver tissue and impair its function …

Liver failure and cirrhosis occur as a result of a variety of chronic hepatic injuries. They
display sequential and overlapping severe pathogenic processes that include severe …

Mesenchymal stem cell (MSC) transplantation is a novel treatment for liver diseases due to
the roles of MSCs in regeneration, fibrosis inhibition and immune regulation. However, the …