Neuroprotective Effects of N-methyl-(2S, 4R)-trans-4-hydroxy-L-proline (NMP) against Amyloid-β-Induced Alzheimer's Disease Mouse Model
Alzheimer's disease (AD), is a progressive neurodegenerative disorder that involves the
deposition of β-amyloid plaques and the clinical symptoms of confusion, memory loss, and …
deposition of β-amyloid plaques and the clinical symptoms of confusion, memory loss, and …
The AMPK-SIRT1-FoxO1-NF-κB signaling pathway participates in hesperetin-mediated neuroprotective effects against traumatic brain injury via the NLRP3 …
H Song, Z Ding, J Chen, T Chen, T Wang… - Immunopharmacology …, 2022 - Taylor & Francis
Background Traumatic brain injury (TBI) induces inflammations that lead to secondary
damage. Hesperetin (Hes) exerts anti-inflammatory activities against central nervous system …
damage. Hesperetin (Hes) exerts anti-inflammatory activities against central nervous system …
Rejuvenation: turning back time by enhancing CISD2
The aging human population with age-associated diseases has become a problem
worldwide. By 2050, the global population of those who are aged 65 years and older will …
worldwide. By 2050, the global population of those who are aged 65 years and older will …
Dapagliflozin/Hesperidin Combination Mitigates Lipopolysaccharide-Induced Alzheimer's Disease in Rats
Alzheimer's disease (AD) is the most common form of neurodegenerative disorders
worldwide. Its pathologic features include massive neuroinflammation with abnormal …
worldwide. Its pathologic features include massive neuroinflammation with abnormal …
Hesperetin, a promising dietary supplement for preventing the development of calcific aortic valve disease
H Zhao, G Xian, J Zeng, G Zhong, D An, Y Peng, D Hu… - Antioxidants, 2022 - mdpi.com
Background: No effective therapeutic agents for calcific aortic valve disease (CAVD) are
available currently. Dietary supplementation has been proposed as a novel treatment …
available currently. Dietary supplementation has been proposed as a novel treatment …
Inhibition of JNK Alleviates Chronic Hypoperfusion‐Related Ischemia Induces Oxidative Stress and Brain Degeneration via Nrf2/HO‐1 and NF‐κB Signaling
Cerebral ischemia is one of the leading causes of neurological disorders. The exact
molecular mechanism related to chronic unilateral cerebral ischemia‐induced …
molecular mechanism related to chronic unilateral cerebral ischemia‐induced …
Neuroinflammation in CNS diseases: Molecular mechanisms and the therapeutic potential of plant derived bioactive molecules
MO Welcome - PharmaNutrition, 2020 - Elsevier
Over the past decades, evidences have consistently shown that Neuroinflammation is a
critical underlying process in a range of CNS diseases, including neurodegenerative …
critical underlying process in a range of CNS diseases, including neurodegenerative …
Metabolic stress alters antioxidant systems, suppresses the adiponectin receptor 1 and induces Alzheimer's like pathology in mice brain
Oxidative stress and insulin resistance play major roles in numerous neurodegenerative
diseases, including Alzheimer's disease (AD). A high-fat diet induces obesity-associated …
diseases, including Alzheimer's disease (AD). A high-fat diet induces obesity-associated …
Effect of hesperidin on fluoride‐induced neurobehavioral and biochemical changes in rats
P Jaiswal, M Mandal, A Mishra - Journal of Biochemical and …, 2020 - Wiley Online Library
Fluoride is the second largest contaminant of drinking water. Fluoride toxicity is a major
concern in the endemic areas where a high amount of fluoride is present in ground water …
concern in the endemic areas where a high amount of fluoride is present in ground water …
MST1 regulates neuronal cell death via JNK/Casp3 signaling pathway in HFD mouse brain and HT22 cells
Oxidative stress has been considered as the main mediator in neurodegenerative diseases.
A high-fat diet (HFD) and metabolic diseases result in oxidative stress generation, leading to …
A high-fat diet (HFD) and metabolic diseases result in oxidative stress generation, leading to …