Involvement of Nrf2 Activation and NF-kB Pathway Inhibition in the Antioxidant and Anti-Inflammatory Effects of Hesperetin in Activated BV-2 Microglial Cells
JA Evans, P Mendonca, KFA Soliman - Brain Sciences, 2023 - mdpi.com
Alzheimer's disease is a progressive neurodegenerative disorder leading to cognitive
decline and memory loss. The incidence of this disease continues to increase due to the …
decline and memory loss. The incidence of this disease continues to increase due to the …
Analyses of physical and chemical compositions of different medicinal specifications of CRPV by use of multiple instrumental techniques combined with multivariate …
Y Wang, W Cui, G Pang, L Xiong, Q Liu, L Xu, H Li… - Molecules, 2022 - mdpi.com
Citri Reticulatae Pericarpium Viride (CRPV) is the processed product of Citrus reticulata
Blanco. We systematically analyzed two CRPV types, Geqingpi (GQP) and Sihuaqingpi …
Blanco. We systematically analyzed two CRPV types, Geqingpi (GQP) and Sihuaqingpi …
[HTML][HTML] Mangiferin exerts neuroprotective activity against lead-induced toxicity and oxidative stress via Nrf2 pathway
H Li, T Lan, C Yun, Z Du, X Luo, E Hao, J Deng - Chinese Herbal Medicines, 2020 - Elsevier
Objective The study was designed to assess the beneficial role of mangiferin (MGN) in lead
(Pb)-induced neurological damages in the activation of Nrf2-governed enzymes, genes and …
(Pb)-induced neurological damages in the activation of Nrf2-governed enzymes, genes and …
Farrerol attenuates glutamate-induced apoptosis in HT22 cells via the Nrf2/heme oxygenase-1 pathway
L Gao, T Wang, D Zhuoma, R Yuan… - Bioscience …, 2023 - academic.oup.com
Farrerol is a flavonoid found in plants with a wide range of pharmacological effects,
including protection and enhancement of nerve cell function, as well as antioxidant and …
including protection and enhancement of nerve cell function, as well as antioxidant and …
[HTML][HTML] Research progress on the mechanism of action of hesperetin in cerebral ischemia: a narrative review
Q Mu, Y Zhang, Q Cheng, H Huang… - Annals of …, 2022 - ncbi.nlm.nih.gov
Methods We conducted a literature search for published manuscripts hesperidin in
ischemia/reperfusion up to December 2021 in common English databases (ie, PubMed …
ischemia/reperfusion up to December 2021 in common English databases (ie, PubMed …
Neuroinflammation and neurodegeneration: The promising protective role of the citrus flavanone hesperetin
E Scoditti - Nutrients, 2020 - mdpi.com
Over the past 20 years, there has been a remarkable increase in the scientific interest in
polyphenols, bioactive compounds naturally present in plant foods and beverages, due to …
polyphenols, bioactive compounds naturally present in plant foods and beverages, due to …
[HTML][HTML] Carminic acid supplementation protects against fructose-induced kidney injury mainly through suppressing inflammation and oxidative stress via improving …
Q Li, Q Xu, J Tan, L Hu, C Ge, M Xu - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Excessive fructose (Fru) intake has become an increased risk for chronic kidney disease
progression. Despite extensive researches that have been performed to develop effective …
progression. Despite extensive researches that have been performed to develop effective …
Recent understanding of the mechanisms of the biological activities of hesperidin and hesperetin and their therapeutic effects on diseases
Z Ji, W Deng, D Chen, Z Liu, Y Shen, J Dai, H Zhou… - Heliyon, 2024 - cell.com
Flavonoids are natural phytochemicals that have therapeutic effects and act in the
prevention of several pathologies. These phytochemicals can be found in lemon, sweet …
prevention of several pathologies. These phytochemicals can be found in lemon, sweet …
[PDF][PDF] Crystal engineering of ionic cocrystals comprising Na/K salts of hesperetin with hesperetin molecules and solubility modulation
S Jin, MM Haskins, CH Deng, CRMO Matos… - IUCrJ, 2023 - journals.iucr.org
Hesperetin (HES) is a weakly acidic flavonoid of topical interest owing to its antiviral
properties. Despite the presence of HES in many dietary supplements, its bioavailability is …
properties. Despite the presence of HES in many dietary supplements, its bioavailability is …
RTA‐408 protects against propofol‐induced cognitive impairment in neonatal mice via the activation of Nrf2 and the inhibition of NF‐κB p65 nuclear translocation
L Zhang, Q Zhou, CL Zhou - Brain and Behavior, 2021 - Wiley Online Library
Objective To explore the effect of RTA‐408 on the propofol‐induced cognitive impairment of
neonatal mice via regulating Nrf2 and NF‐κB p65 nuclear translocation. Methods C57BL/6 …
neonatal mice via regulating Nrf2 and NF‐κB p65 nuclear translocation. Methods C57BL/6 …