Although first identified over 70 years ago, Klinefelter syndrome (KS) continues to pose
substantial diagnostic challenges, as many patients are still misdiagnosed, or remain …

Incidence and prevalence of hypopituitarism are estimated to be 4· 2 per 100 000 per year
and 45· 5 per 100 000, respectively. Although the clinical symptoms of this disorder are …

ABSTRACT The Standards of Care (SOC) for the Health of Transsexual, Transgender, and
Gender Nonconforming People is a publication of the World Professional Association for …

OBJECTIVE—The aim of our study was to assess the prevalence of clinical hypogonadism,
based on both symptoms and biochemical available measures of testosterone deficiency, in …

Context: Although attention and concern about health disorders in aging men have been
growing, the structure of psychological and somatic complaints of actual patients, not …

ABSTRACT Introduction In 2014, the International Society for Sexual Medicine (ISSM)
convened a panel of experts to develop an evidence‐based process of care for the …

Steroid hormones are synthesized in the adrenal gland, gonads, placenta and brain and are
critical for normal reproductive function and bodily homeostasis. The steroidogenic acute …

The term Late‐onset hypogonadism (LOH) was coined in 2002 and defined as a disease
entity in the ISA, ISSAM, EAU, EAA and ASA endorsed Recommendations for Investigation …

An international consensus document was recently published and provides guidance on the
diagnosis, treatment and monitoring of late-onset hypogonadism (LOH) in men. The …

Introduction Gender dysphoria is characterized by a strong discomfort with the gender
assigned at birth and the urge to live as a member of the opposite gender. The acquisition of …