Hippocampal volume increase in response to aerobic exercise has been consistently
observed in animal models. However, the evidence from human studies is equivocal. We …

Abstract The original Human Connectome Project yielded a rich data set on structural and
functional connectivity in a large sample of healthy young adults using improved methods of …

Little is still known about the neuroanatomical substrates related to changes in specific
cognitive abilities in the course of healthy aging, and the existing evidence is predominantly …

The availability of neuroimaging technology has spurred a marked increase in the human
cognitive neuroscience literature, including the study of cognitive ageing. Although there is a …

Episodic memory and working memory decline with advancing age. Nevertheless, large-
scale population-based studies document well-preserved memory functioning in some older …

Background Mild cognitive impairment (MCI) is a well-recognised risk factor for dementia
and represents a vital opportunity for intervening. Exercise is a promising strategy for …

Cognitive performance, including performance on working memory (WM) tasks declines with
age. Changes in brain activations are one presumed contributor to WM decline in the …

Alterations in inhibitory interneurons contribute to cognitive deficits associated with several
psychiatric and neurological diseases. Phasic and tonic inhibition imparted by γ …

Aging is associated with decreased resting-state functional connectivity (RSFC) within the
default mode network (DMN), but most functional imaging studies have restricted the …

Normal aging is associated with cognitive decline and underlying brain dysfunction.
Previous studies concentrated less on brain network changes at a systems level. Our goal …